A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra

CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …

Edited 1H magnetic resonance spectroscopy in vivo: Methods and metabolites

AD Harris, MG Saleh… - Magnetic resonance in …, 2017 - Wiley Online Library
The Proton magnetic resonance (1H‐MRS) spectrum contains information about the
concentration of tissue metabolites within a predefined region of interest (a voxel). The …

Intact metabolite spectrum mining by deep learning in proton magnetic resonance spectroscopy of the brain

HH Lee, H Kim - Magnetic resonance in medicine, 2019 - Wiley Online Library
Purpose To develop a robust method for brain metabolite quantification in proton magnetic
resonance spectroscopy (1H‐MRS) using a convolutional neural network (CNN) that maps …

Proton and multinuclear magnetic resonance spectroscopy in the human brain at ultra-high field strength: a review

A Henning - Neuroimage, 2018 - Elsevier
Abstract Magnetic Resonance Spectroscopy (MRS) allows for a non-invasive and non-
ionizing determination of in vivo tissue concentrations and metabolic turn-over rates of more …

HERMES: Hadamard encoding and reconstruction of MEGA‐edited spectroscopy

KL Chan, NAJ Puts, M Schär, PB Barker… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose To investigate a novel Hadamard‐encoded spectral editing scheme and evaluate
its performance in simultaneously quantifying N‐acetyl aspartate (NAA) and N‐acetyl …

T2 measurement of J‐coupled metabolites in the human brain at 3T

SK Ganji, A Banerjee, AM Patel, YD Zhao… - NMR in …, 2012 - Wiley Online Library
Proton T2 relaxation times of metabolites in the human brain were measured using point
resolved spectroscopy at 3T in vivo. Four echo times (54, 112, 246 and 374 ms) were …

Methodology for improved detection of low concentration metabolites in MRS: optimised combination of signals from multi-element coil arrays

EL Hall, MC Stephenson, D Price, PG Morris - Neuroimage, 2014 - Elsevier
State of the art magnetic resonance imaging (MRI) scanners are generally equipped with
multi-element receive coils; 16 or 32 channel coils are common. Their development has …

Multinuclear magnetic resonance spectroscopy at ultra-high-field: assessing human cerebral metabolism in healthy and diseased states

P Veeraiah, JFA Jansen - Metabolites, 2023 - mdpi.com
The brain is a highly energetic organ. Although the brain can consume metabolic substrates,
such as lactate, glycogen, and ketone bodies, the energy metabolism in a healthy adult …

Measurement of regional variation of GABA in the human brain by optimized point‐resolved spectroscopy at 7 T in vivo

SK Ganji, Z An, A Banerjee, A Madan… - NMR in …, 2014 - Wiley Online Library
The 1H resonances of γ‐aminobutyric acid (GABA) in the human brain in vivo are
extensively overlapped with the neighboring abundant resonances of other metabolites and …

Separate N‐acetyl aspartyl glutamate, N‐acetyl aspartate, aspartate, and glutamate quantification after pediatric mild traumatic brain injury in the acute phase

P Menshchikov, A Ivantsova… - Magnetic …, 2020 - Wiley Online Library
Purpose To separately measure N‐acetyl aspartul glutamate (NAAG), N‐acetyl aspartate
(NAA), aspartate (Asp), and glutamate (Glu) concentrations in white matter (WM) using J …