Spatial regulation of RNA plays a critical role in gene expression regulation and cellular
function. Understanding spatially resolved RNA dynamics and translation is vital for bringing …

Ribosomes were known to be multicomponent complexes as early as the 1960s.
Nonetheless, the prevailing view for decades considered active ribosomes to be a …

Different regions of RNA molecules can often engage in specific interactions with distinct
RNA-binding proteins (RBPs), giving rise to diverse modalities of RNA regulation and …

Ribosomal RNA (rRNA) genes exist in multiple copies arranged in tandem arrays known as
ribosomal DNA (rDNA). The total number of gene copies is variable, and the mechanisms …

The traditional perception of ribosomes as uniform molecular machines has been
revolutionized by recent discoveries, revealing a complex landscape of ribosomal …

Although genome‐scale analyses have provided insights into the connection between
genetic variability and complex human phenotypes, much trait variation is still not fully …

In this issue of Cell Genomics, Rothschild et al. 1 reveal how ribosomal RNA diversity
impacts ribosome structure and its implications for health and disease. Their innovative …

Examination of all publicly available Oryctolagus cuniculus (rabbit) ribosome cryo-EM
structures reveals numerous confusing inconsistencies. First, there are a plethora of single …

The ribosome is one of the core macromolecules in the cell. The ribosomal RNAs (rRNA),
which are essential components of the ribosome, are coded by the multi-copy ribosomal …

Cell survival, growth, and proliferation are dependent on ribosomal protein synthesis.
Ribosome biogenesis is thus a highly regulated process to preserve cell function and …