Caenorhabditis elegans survives on ephemeral food sources in the wild, and the species
has a variety of adaptive responses to starvation. These features of its life history make the …

Adaptive neuroplasticity is a pivotal mechanism for healthy brain development and
maintenance, as well as its restoration in disease-and age-associated decline. Management …

Pulmonary hypertension (PH) represents a group of disorders characterized by elevated
mean pulmonary artery (PA) pressure, progressive right ventricular failure, and often death …

Cooperation and cheating are widespread evolutionary strategies. While cheating confers
an advantage to individual entities within a group, competition between groups favors …

The nematode C. elegans is a leading model to investigate the mechanisms of stress-
induced behavioral changes coupled with biochemical mechanisms. Our group has …

Autophagy is being studied intensively in Caenorhabditis elegans in the context of protein
homeostasis and aging. However, in contrast to the yeast and mammalian autophagosomal …

The feeling of hunger or satiety results from integration of the sensory nervous system with
other physiological and metabolic cues. This regulates food intake, maintains homeostasis …

Abstract Downregulating miR-217-5p could protect cardiomyocytes against
ischemia/reperfusion (I/R) injury, but its role in restoring mitochondrial function of I/R-injured …

Autophagy, or cellular self-digestion, is an essential cellular process imperative for energy
homeostasis, development, differentiation, and survival. However, the intrinsic factors that …

Mitochondria perform many essential cellular functions including energy production, calcium
homeostasis, transduction of metabolic and stress signals, and mediating cell survival and …