Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

JAHR Claassen, DHJ Thijssen… - Physiological …, 2021‏ - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Sit less and move more for cardiovascular health: emerging insights and opportunities

DW Dunstan, S Dogra, SE Carter… - Nature Reviews Cardiology, 2021‏ - nature.com
Sedentary behaviour—put simply, too much sitting, as a distinct concept from too little
exercise—is a novel determinant of cardiovascular risk. This definition provides a …

The neurovasculome: key roles in brain health and cognitive impairment: a scientific statement from the American Heart Association/American Stroke Association

C Iadecola, EE Smith, J Anrather, C Gu, A Mishra… - Stroke, 2023‏ - Am Heart Assoc
Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …

Transcranial Doppler ultrasound: technique and application

S Purkayastha, F Sorond - Seminars in neurology, 2012‏ - thieme-connect.com
Transcranial Doppler (TCD) ultrasound provides rapid, noninvasive, real-time measures of
cerebrovascular function. TCD can be used to measure flow velocity in the basal arteries of …

[HTML][HTML] Regular walking breaks prevent the decline in cerebral blood flow associated with prolonged sitting

SE Carter, R Draijer, SM Holder… - Journal of applied …, 2018‏ - journals.physiology.org
Decreased cerebrovascular blood flow and function are associated with lower cognitive
functioning and increased risk of neurodegenerative diseases. Prolonged sitting impairs …

Cerebral blood flow in mild cognitive impairment and Alzheimer's disease: A systematic review and meta-analysis

H Zhang, Y Wang, D Lyu, Y Li, W Li, Q Wang… - Ageing research …, 2021‏ - Elsevier
Background Reduced cerebral blood flow (CBF) contributes to the pathophysiology of
Alzheimer's disease (AD). However, it is unclear whether there is a spatial-temporal-specific …

Effects of age and sex on middle cerebral artery blood velocity and flow pulsatility index across the adult lifespan

MR Alwatban, SE Aaron, CS Kaufman… - Journal of Applied …, 2021‏ - journals.physiology.org
Reduced middle cerebral artery blood velocity (MCAv) and flow pulsatility are contributors to
age-related cerebrovascular disease pathogenesis. It is unknown whether the rate of …

[HTML][HTML] Retinal microvascular network attenuation in Alzheimer's disease

MA Williams, AJ McGowan, CR Cardwell… - Alzheimer's & Dementia …, 2015‏ - Elsevier
Introduction Cerebral small-vessel disease has been implicated in the development of
Alzheimer's disease (AD). The retinal microvasculature enables the noninvasive …

Cerebral hemodynamics in mild cognitive impairment: a systematic review

L Beishon, VJ Haunton, RB Panerai… - Journal of Alzheimer's …, 2017‏ - content.iospress.com
Background: The incidence of dementia is projected to rise over the coming decades, but
with no sensitive diagnostic tests available. Vascular pathology precedes the deposition of …