Advances in deep eutectic solvents and water: applications in metal-and biocatalyzed processes, in the synthesis of APIs, and other biologically active compounds

L Cicco, G Dilauro, FM Perna, P Vitale… - Organic & Biomolecular …, 2021 - pubs.rsc.org
Owing to a growing awareness towards environmental impact, the search for “greener”,
safer, and cost-effective solvents able to replace petroleum-derived solvents has never been …

Soluplus® as a solubilizing excipient for poorly water-soluble drugs: Recent advances in formulation strategies and pharmaceutical product features

MS Attia, A Elshahat, A Hamdy, AM Fathi… - Journal of Drug Delivery …, 2023 - Elsevier
Since the emergence of Soluplus®(SOL) as a commercial graft copolymer, several
publications have been issued on its promising potential as a solubilizing excipient that …

Tailor-made solvents for microbial carotenoids recovery

CU Mussagy, HU Hucke, NF Ramos, HF Ribeiro… - Applied Microbiology …, 2024 - Springer
In recent years, microbial carotenoids have emerged as a promising alternative for the
pharmaceutical and food industries, particularly in promoting human health due to their …

[HTML][HTML] Ionic liquids and deep eutectic solvents as sustainable alternatives for efficient extraction of phenolic compounds from mate leaves

AACT Hijo, C Alves, FO Farias, VS Peixoto… - Food Research …, 2022 - Elsevier
Mate leaves are highly appreciated in south and central America as food ingredient for tea
preparation. Their nutritional importance, due to their high content of polyphenols and other …

Extraction and purification of curcuminoids from Curcuma longa using microwave assisted deep eutectic solvent based system and cost estimation

SS Patil, VK Rathod - Process Biochemistry, 2023 - Elsevier
Deep eutectic solvents (DESs) are explored to develop sustainable and green processes as
an alternative to conventional solvents. Likewise, microwave-assisted extraction (MAE) is a …

Deep eutectic solvents as an alternative for extraction of flavonoids from soybean (Glycine max (L) Merrill) and okara: An experimental and computational approach …

RSB Ferreira, FO Farias, EJS de Araujo… - Food Research …, 2023 - Elsevier
In this study, different Deep Eutectic Solvents based on choline chloride ([Ch] Cl) with
carboxylic acids, sugars, and glycerol, were investigated as alternative solvents for the …

[HTML][HTML] Solvent screening for solubility enhancement of theophylline in neat, binary and ternary NADES solvents: New measurements and ensemble machine …

P Cysewski, T Jeliński, P Cymerman… - International Journal of …, 2021 - mdpi.com
Theophylline, a typical representative of active pharmaceutical ingredients, was selected to
study the characteristics of experimental and theoretical solubility measured at 25° C in a …

Natural Deep Eutectic Solvent-Based Ultrasound-Assisted Extraction of Flavonoids from Fagopyrum tataricum Bran

Z Xu, X Da, J Qu, S **ao - Separations, 2024 - mdpi.com
In this study, eleven kinds of flavonoids were identified from F. tataricum bran (FTB) by UPLC-
Q-TOF-MS, and HPLC-DAD analysis revealed that four compounds, including rutin …

Extraction of triterpene acids from loquat leaves via a novel hydrophobic deep eutectic solvent screened by COSMO-SAC model

L Huang, Y Guo, T **, K Yan, X Liu, S He, L Li… - Journal of Cleaner …, 2023 - Elsevier
Triterpene acids (TTAs) have promising applications in functional food, medicine and other
fields. Here, ultrasonic-assisted hydrophobic deep eutectic solvent (HDES) extraction was …

Modifiers based on deep eutectic mixtures: A case study for the extraction of anthocyanins from black bean hulls using high pressure fluid technology

M Kuasnei, JP Wojeicchowski, NH Santos… - The Journal of …, 2022 - Elsevier
Deep eutectic solvents (DES) were selected as water modifiers to perform the subcritical
water extraction (SWE), aiming at the selective extraction of anthocyanins from black beans …