The past few years have brought substantial progress toward understanding how human
cytomegalovirus (HCMV) enters the remarkably wide spectrum of cell types and tissues that …

Congenital cytomegalovirus (CMV) infection is the leading infectious cause of mental
retardation and hearing loss in the developed world. In recent years, there has been an …

The genetic content of wild-type human cytomegalovirus was investigated by sequencing
the 235 645 bp genome of a low passage strain (Merlin). Substantial regions of the genome …

Human cytomegalovirus replicates in many different cell types, including epithelial cells,
endothelial cells, and fibroblasts. However, laboratory strains of the virus, many of which …

Six strains of human cytomegalovirus have been sequenced, including two laboratory
strains (AD169 and Towne) that have been extensively passaged in fibroblasts and four …

Human cytomegalovirus (HCMV), a ubiquitous human pathogen, is the leading cause of
birth defects and morbidity in immunocompromised patients and a potential trigger for …

Human cytomegalovirus (HCMV) strain TB40/E, replicates efficiently, exhibits a broad cell
tropism and is widely used for infection of endothelial cells and monocyte-derived cells yet …

The entry of human cytomegalovirus (HCMV) into biologically relevant epithelial and
endothelial cells involves endocytosis followed by low-pH-dependent fusion. This entry …

Epithelial cells are one of the prominent cell types infected by human cytomegalovirus
(HCMV) within its host. However, many cultured epithelial cells, such as ARPE-19 retinal …

Human cytomegalovirus (HCMV) in clinical material cannot replicate efficiently in vitro until it
has adapted by mutation. Consequently, wild-type HCMV differ fundamentally from the …