Recent development of synthetic preparation methods for guanidines via transition metal catalysis

WX Zhang, L Xu, Z ** - Chemical Communications, 2015‏ - pubs.rsc.org
Multisubstituted guanidines have received much attention because of important applications
in many fields, such as pharmaceutics, organometallic and coordination chemistry, and …

[PDF][PDF] Recent developments in guanylating agents

AR Katritzky, BV Rogovoy - Arkivoc, 2005‏ - pdf.lookchemmall.com
Guanidines are important molecules with a wide range of interesting properties. In this
overview we summarize recent advances in the development of guanylating reagents which …

Triurethane-protected guanidines and triflyldiurethane-protected guanidines: new reagents for guanidinylation reactions

K Feichtinger, HL Sings, TJ Baker… - The Journal of …, 1998‏ - ACS Publications
New guanidinylation reagents are reported. These reagents consist of N, N ', N ''-tri-Boc-
guanidine (1) and N, N ', N ''-tri-Cbz-guanidine (2), which allow for the facile conversion of …

The chemistry and biology of guanidine secondary metabolites

RGS Berlinck, DI Bernardi, T Fill… - Natural Product …, 2021‏ - pubs.rsc.org
Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine
invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal …

The tethered Biginelli condensation in natural product synthesis

ZD Aron, LE Overman - Chemical Communications, 2004‏ - pubs.rsc.org
The tethered Biginelli condensation in natural product synthesis - Chemical
Communications (RSC Publishing) DOI:10.1039/B309910E Royal Society of Chemistry …

A unique high-diversity natural product collection as a reservoir of new therapeutic leads

F Ghirga, D Quaglio, M Mori, S Cammarone… - Organic Chemistry …, 2021‏ - pubs.rsc.org
Plants represent a rich source of structurally diverse secondary metabolites, which can be
exploited in the development of new clinically important compounds. Indeed, due to their …

Autocatalytic and oscillatory reaction networks that form guanidines and products of their cyclization

AI Novichkov, AI Hanopolskyi, X Miao… - Nature …, 2021‏ - nature.com
Autocatalytic and oscillatory networks of organic reactions are important for designing life-
inspired materials and for better understanding the emergence of life on Earth; however, the …

Concise synthesis of guanidine-containing heterocycles using the Biginelli reaction

BL Nilsson, LE Overman - The Journal of organic chemistry, 2006‏ - ACS Publications
Two general methods for the synthesis of 2-imino-5-carboxy-3, 4-dihydropyrimidines were
developed using the three-component Biginelli reaction. The first method utilizes pyrazole …

Hypervalent iodine-mediated vicinal syn diazidation: Application to the total synthesis of (±)-dibromophakellstatin

R Chung, E Yu, CD Incarvito, DJ Austin - Organic Letters, 2004‏ - ACS Publications
Hypervalent Iodine-Mediated Vicinal Syn Diazidation: Application to the Total Synthesis of (±)-Dibromophakellstatin
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Application of the tethered Biginelli reaction for enantioselective synthesis of batzelladine alkaloids. Absolute configuration of the tricyclic guanidine portion of …

AS Franklin, SK Ly, GH Mackin… - The Journal of …, 1999‏ - ACS Publications
Tethered Biginelli condensation of enantioenriched hexahydropyrrolopyrimidines 8 with β-
ketoesters provides efficient asymmetric access to tricyclic guanidines 9 having a syn …