Older adults with subjective cognitive decline (SCD) in the absence of objective
neuropsychological dysfunction are increasingly viewed as at risk for non-normative …

Research increasingly suggests that subjective cognitive decline (SCD) in older adults, in
the absence of objective cognitive dysfunction or depression, may be a harbinger of non …

Alzheimer disease (AD) is biologically defined by the presence of β-amyloid-containing
plaques and tau-containing neurofibrillary tangles. AD is a genetic and sporadic …

Background Alzheimer's disease (AD) pathology begins several years before the clinical
onset. The long preclinical phase is composed of three stages according to the …

Background Cerebral small vessel disease, a common cause of vascular dementia, is often
considered clinically silent before dementia or stroke become apparent. However, some …

Identification of subjects at the early stages of Alzheimer's disease (AD) is fundamental for
drug development and possible intervention or prevention of cognitive decline. The concept …

Introduction This study assessed apolipoprotein E (APOE) ε4 carrier status effects on
Alzheimer's disease imaging and cerebrospinal fluid (CSF) biomarkers in cognitively normal …