Objective To assess the associations between statins and adverse events in primary
prevention of cardiovascular disease and to examine how the associations vary by type and …

Importance The effects of bempedoic acid on cardiovascular outcomes in statin-intolerant
patients without a prior cardiovascular event (primary prevention) have not been fully …

Clinical question In adults with low density lipoprotein (LDL) cholesterol levels> 1.8 mmol/L
(> 70 mg/dL) who are already taking the maximum dose of statins or are intolerant to statins …

Thanks to advances in the field over the years, HIV/AIDS has now become a manageable
chronic condition. Nevertheless, a new set of HIV-associated complications has emerged …

Importance Many patients at high cardiovascular risk—women more commonly than men—
are not receiving statins. Anecdotally, it is common for patients to not accept statin therapy …

Background An increasing number of patients with a peripheral arterial occlusive disease
were put on statins during the past years. This study assessed whether statin therapy was …

Objectives In the context of limited evidence on statin use in primary cardiovascular
prevention in older adults, we assessed physician perspectives on decision-making about …

Aims Studies in primary healthcare (PHC) assessing the effect of primary prevention with
statins on mortality and cardiovascular disease (CVD) are scarce. This study aimed to …

Background Limited information is available on detailed sex/age-specific associations
between low-density lipoprotein cholesterol (LDL-C) and cardiovascular disease (CVD) …

Background Despite their proven efficacy to reduce cardiovascular disease, statin
medication use remains low in individuals at high risk of cardiovascular disease considering …