Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes
substantial morbidity and mortality predominantly in paediatric populations in low-and …

Abstract Purpose of Review Review recent developments pertaining to the epidemiology,
molecular pathogenesis, and sequelae of enterotoxigenic Escherichia coli (ETEC) infections …

In the decade since oral rotavirus vaccines (ORV) were recommended by the World Health
Organization for universal inclusion in all national immunization programs, significant yet …

Background Oral vaccines underperform in low-income and middle-income countries
compared with in high-income countries. Whether interventions can improve oral vaccine …

Identifying risk factors for impaired oral rotavirus vaccine (ORV) efficacy in low-income
countries may lead to improvements in vaccine design and delivery. In this prospective …

Live, oral rotavirus vaccines are more effective at preventing rotavirus disease in countries
with low child mortality compared with high child mortality. Among several hypotheses …

Background: Environmental enteric dysfunction (EED), characterized by altered intestinal
permeability/inflammation, microbial translocation, and systemic inflammation (SI), may be a …

Background Environmental enteropathy (EE) contributes to impaired linear growth
(stunting), in millions of children worldwide. We have previously reported that confocal laser …

Background A three-dose, oral rotavirus vaccine (Rotavac) was introduced in the universal
immunization program in India in 2016. A prelicensure trial involving 6799 infants was not …

Environmental enteropathy (EE) is a subclinical condition of the small intestine that is highly
prevalent in low-and middle-income countries. It is thought to be a key contributing factor to …