PARP inhibitors: clinical relevance, mechanisms of action and tumor resistance

M Rose, JT Burgess, K O'Byrne, DJ Richard… - Frontiers in cell and …, 2020 - frontiersin.org
The Poly (ADP-ribose) polymerase (PARP) family has many essential functions in cellular
processes, including the regulation of transcription, apoptosis and the DNA damage …

Current status and prospect of ZIF-based materials for breast cancer treatment

Y Zeng, D Liao, X Kong, Q Huang, M Zhong… - Colloids and Surfaces B …, 2023 - Elsevier
Breast cancer, one of the three most life-threatening cancers in modern times, must be
explored for treatments with low side effects and practical efficacy. Metal organic framework …

Recent advances of nucleic acid-based cancer biomarkers and biosensors

J Zhao, K **a, P He, G Wei, X Zhou, X Zhang - Coordination Chemistry …, 2023 - Elsevier
Nucleic acid-based cancer biomarkers (NABCBs) have emerged as a notable and
continuously captivating research focal point within the domain of oncology. As a result …

Exploring biomarkers in breast cancer: Hallmarks of diagnosis, treatment, and follow-up in clinical practice

L Lopez-Gonzalez, A Sanchez Cendra… - Medicina, 2024 - mdpi.com
Breast cancer is a prevalent malignancy in the present day, particularly affecting women as
one of the most common forms of cancer. A significant portion of patients initially present …

Therapeutic evolution in HR+/HER2-breast cancer: from targeted therapy to endocrine therapy

LQ Cao, H Sun, Y **e, H Patel, L Bo, H Lin… - Frontiers in …, 2024 - frontiersin.org
Breast cancer, a complex and varied disease, has four distinct subtypes based on estrogen
receptor and human epidermal growth factor receptor 2 (HER2) levels, among which a …

The relationship between tobacco and breast cancer incidence: A systematic review and meta-analysis of observational studies

Y He, Y Si, X Li, J Hong, C Yu, N He - Frontiers in oncology, 2022 - frontiersin.org
Background The effect of tobacco on breast cancer (BC) is controversial. The purpose of this
study was to investigate the relationship between tobacco and BC. Methods A search was …

Identifying actionable druggable targets for breast cancer: Mendelian randomization and population-based analyses

N Zhang, Y Li, J Sundquist, K Sundquist, J Ji - EBioMedicine, 2023 - thelancet.com
Background Drug repurposing provides a cost-effective approach to address the need for
breast cancer prevention and therapeutics. We aimed to identify actionable druggable …

A fully 3D-printed versatile tumor-on-a-chip allows multi-drug screening and correlation with clinical outcomes for personalized medicine

E Steinberg, R Friedman, Y Goldstein… - Communications …, 2023 - nature.com
Optimal clinical outcomes in cancer treatments could be achieved through the development
of reliable, precise ex vivo tumor models that function as drug screening platforms for patient …

The relationship between dairy products intake and breast cancer incidence: a meta-analysis of observational studies

Y He, Q Tao, F Zhou, Y Si, R Fu, B Xu, J Xu, X Li… - BMC cancer, 2021 - Springer
Background The effect of dairy products intake on breast cancer (BC) is highly controversial.
This study aims to investigate the relationship between dairy intake and BC incidence …

Male breast Cancer: current scenario and future perspectives

A Chidambaram, R Prabhakaran… - … in Cancer Research …, 2024 - journals.sagepub.com
Male breast cancer (MBC), one of the rare types of cancer among men where the global
incidence rate is 1.8% of all breast cancers cases with a yearly increase in a pace of 1.1 …