The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer

S Chakraborty, S Kaur, S Guha, SK Batra - Biochimica et Biophysica Acta …, 2012 - Elsevier
Neutrophil gelatinase associated lipocalin (NGAL), also known as oncogene 24p3,
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …

[HTML][HTML] Biomarkers in chronic kidney disease: a review

RG Fassett, SK Venuthurupalli, GC Gobe… - Kidney international, 2011 - Elsevier
Chronic kidney disease (CKD) is a major public health problem. The classification of CKD by
KDOQI and KDIGO and the routine eGFR reporting have resulted in increased identification …

Reactive astrocytes secrete lcn2 to promote neuron death

F Bi, C Huang, J Tong, G Qiu… - Proceedings of the …, 2013 - National Acad Sciences
Glial reaction is a common feature of neurodegenerative diseases. Recent studies have
suggested that reactive astrocytes gain neurotoxic properties, but exactly how reactive …

Urinary kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin as indicators of tubular damage in normoalbuminuric patients with type 2 diabetes

JAM de Carvalho, E Tatsch, BS Hausen, YS Bollick… - Clinical …, 2016 - Elsevier
Objectives Renal dysfunction has been reported in normoalbuminuric patients,
demonstrating the necessity to improve the diagnostic and prognostic tools for diabetic …

[PDF][PDF] The role of oxidative stress in the metabolic syndrome

A Whaley-Connell, PA McCullough… - Reviews in …, 2011 - article.imrpress.com
Loss of reduction-oxidation (redox) homeostasis and generation of excess free oxygen
radicals play an important role in the pathogenesis of diabetes, hypertension, and …

Proteomic biomarkers in kidney disease: issues in development and implementation

H Mischak, C Delles, A Vlahou… - Nature Reviews …, 2015 - nature.com
Proteomic biomarkers offer the hope of improving the management of patients with kidney
diseases by enabling more accurate and earlier detection of renal pathology than is …

[HTML][HTML] Neutrophil gelatinase-associated lipocalin (NGAL) is associated with symptomatic carotid atherosclerosis and drives pro-inflammatory state in vitro

W Eilenberg, S Stojkovic, A Piechota-Polanczyk… - European Journal of …, 2016 - Elsevier
Objective Neutrophil gelatinase-associated lipocalin (NGAL), a protein found in activated
neutrophils, is expressed in kidney tubule cells in response to noxious stimuli, and is thus …

Lipocalin 2 regulates iron homeostasis, neuroinflammation, and insulin resistance in the brains of patients with dementia: Evidence from the current literature

D Lim, J Jeong, J Song - CNS neuroscience & therapeutics, 2021 - Wiley Online Library
Dementia accompanied by memory loss is considered one of the most common
neurodegenerative diseases worldwide, and its prevalence is gradually increasing. Known …

Prognostic value of plasma neutrophil gelatinase–associated lipocalin for mortality in patients with heart failure

VM van Deursen, K Damman, AA Voors… - Circulation: Heart …, 2014 - Am Heart Assoc
Background—In patients with heart failure, renal dysfunction is associated with a poor
outcome. We aimed to assess the prognostic value of plasma neutrophil gelatinase …

Novel biomarkers in chronic heart failure

T Ahmad, M Fiuzat, GM Felker… - Nature Reviews Cardiology, 2012 - nature.com
Understanding of chronic heart failure (HF) has progressed from a syndrome of disordered
hemodynamics caused by alterations in the structure of the heart to one that involves …