[HTML][HTML] Transcriptomes of Dravet syndrome iPSC derived GABAergic cells reveal dysregulated pathways for chromatin remodeling and neurodevelopment

J Schuster, L Laan, J Klar, Z **, M Huss, S Korol… - Neurobiology of …, 2019 - Elsevier
Dravet syndrome (DS) is an early onset refractory epilepsy typically caused by de novo
heterozygous variants in SCN1A encoding the α-subunit of the neuronal sodium channel Na …

Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells

A Congras, H Barasc, K Canale-Tabet… - Scientific Reports, 2016 - nature.com
The pig is an emerging animal model, complementary to rodents for basic research and for
biomedical and agronomical purposes. However despite the progress made on mouse and …

Current reprogramming systems in regenerative medicine: from somatic cells to induced pluripotent stem cells

C Hu, L Li - Regenerative medicine, 2016 - Taylor & Francis
Induced pluripotent stem cells (iPSCs) paved the way for research fields including cell
therapy, drug screening, disease modeling and the mechanism of embryonic development …

[HTML][HTML] Mowat-Wilson syndrome: Generation of two human iPS cell lines (UUIGPi004A and UUIGPi005A) from siblings with a truncating ZEB2 gene variant

J Schuster, M Sobol, A Fatima, A Khalfallah, L Laan… - Stem Cell Research, 2019 - Elsevier
Mowat-Wilson syndrome (MWS) is a complex developmental syndrome caused by
heterozygous mutations in the Zinc finger E-box-binding homeobox 2 gene (ZEB2). We …