A maternal high-fat diet affects offspring neurodevelopment with long-term consequences on
their brain health and behavior. During the past three decades, obesity has rapidly …

The inbred mouse strain C57BL/6 has been widely used as a background strain for
spontaneous and induced mutations. Developed in the 1930s, the C57BL/6 strain diverged …

Postprandial IL-1β surges are predominant in the white adipose tissue (WAT), but its
consequences are unknown. Here, we investigate the role of IL-1β in WAT energy storage …

Astaxanthin is a member of the carotenoid family that is found abundantly in marine
organisms, and has been gaining attention in recent years due to its varied biological …

Insulin resistance (IR) is a complex pathological condition central to metabolic diseases
such as type 2 diabetes mellitus (T2DM), cardiovascular disease, non-alcoholic fatty liver …

Research on Alzheimer's disease (AD) has classically focused on alterations that occur in
the brain and their intra-and extracellular neuropathological hallmarks. However, the oxi …

Obesity and its associated metabolic diseases are currently a priority research area. The
increase in global prevalence at different ages is having an enormous economic and health …

Animal models play a critical role in establishing causal relationships between gut
microbiota and disease. The laboratory mouse is widely used to study the role of microbes in …

The mouse is the most commonly used model species in biomedical research. Just as
human physical and mental health are influenced by the commensal gut bacteria, mouse …

Nonalcoholic fatty liver disease (NAFLD) has become the main cause of chronic liver
disease worldwide, and the increasing trend of NAFLD has burdened the healthcare system …