Macrophages represent a heterogeneous cell population and are known to display a
remarkable plasticity. In response to distinct micro-environmental stimuli, eg, tumor stroma …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis, represents a chronic and
progressive disease with high mortality and limited therapeutic options. Excessive …

Review on three IL-4-related branch points for immune regulation: alternative splicing of IL-
4, differential receptor engagement, and differential regulation of macrophage activation by …

Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …

Rationale: Recently, models of macrophage activation have been revised. Macrophages
stimulated with Th2 cytokines have been classified as alternatively activated. Objectives …

Objective Interstitial lung disease (ILD) in systemic sclerosis (SS c) runs a highly variable
course, and prediction tools are highly desired. The aim of this study was to assess the …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Objective Systemic sclerosis (SSc)–related interstitial lung disease (ILD) is one of the
leading causes of mortality. We undertook this study to analyze the gene expression of lung …

Idiopathic pulmonary fibrosis (IPF) is a progressive chronic disorder characterized by
activation of fibroblasts and overproduction of extracellular matrix (ECM). Caveolin-1 (cav-1) …