Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Recent advances in microfluidic technology for bioanalysis and diagnostics

SF Berlanda, M Breitfeld, CL Dietsche… - Analytical …, 2020 - ACS Publications
Microfluidics has become a mature technology, providing an excellent toolbox for the
handling and manipulation of fluid samples, suspended cells, and particles. About 30 years …

Analytical device miniaturization for the detection of circulating biomarkers

A Natalia, L Zhang, NR Sundah, Y Zhang… - Nature Reviews …, 2023 - nature.com
Diverse (sub) cellular materials are secreted by cells into the systemic circulation at different
stages of disease progression. These circulating biomarkers include whole cells, such as …

Integrated “lab-on-a-chip” microfluidic systems for isolation, enrichment, and analysis of cancer biomarkers

S Surappa, P Multani, U Parlatan, PD Sinawang… - Lab on a Chip, 2023 - pubs.rsc.org
The liquid biopsy has garnered considerable attention as a complementary clinical tool for
the early detection, molecular characterization and monitoring of cancer over the past …

Aptamers in biomedicine: Selection strategies and recent advances

G Ștefan, O Hosu, K De Wael, MJ Lobo-Castañón… - Electrochimica …, 2021 - Elsevier
Aptamers have come in the spotlight as bio-mimetic molecular recognition elements in the
field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics …

Recent advances for cancer detection and treatment by microfluidic technology, review and update

N Bargahi, S Ghasemali, S Jahandar-Lashaki… - Biological Procedures …, 2022 - Springer
Numerous cancer-associated deaths are owing to a lack of effective diagnostic and
therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a …

[HTML][HTML] Recent progress in aptamer-based microfluidics for the detection of circulating tumor cells and extracellular vesicles

D Sun, Y Ma, M Wu, Z Chen, L Zhang, J Lu - Journal of Pharmaceutical …, 2023 - Elsevier
Liquid biopsy is a technology that exhibits potential to detect cancer early, monitor therapies,
and predict cancer prognosis due to its unique characteristics, including noninvasive …

Recent advances in microfluidic platforms applied in cancer metastasis: Circulating tumor cells'(CTCs) isolation and tumor‐on‐a‐chip

Z Lin, G Luo, W Du, T Kong, C Liu, Z Liu - Small, 2020 - Wiley Online Library
Cancer remains the leading cause of death worldwide despite the enormous efforts that are
made in the development of cancer biology and anticancer therapeutic treatment …

Lab-on-a-chip systems for cancer biomarker diagnosis

C Özyurt, İ Uludağ, B İnce, MK Sezgintürk - Journal of Pharmaceutical and …, 2023 - Elsevier
Abstract Lab-on-a-chip (LOC) or micro total analysis system is one of the microfluidic
technologies defined as the adaptation, miniaturization, integration, and automation of …

Saliva-based COVID-19 detection: A rapid antigen test of SARS-CoV-2 nucleocapsid protein using an electrical-double-layer gated field-effect transistor-based …

PH Chen, CC Huang, CC Wu, PH Chen… - Sensors and Actuators B …, 2022 - Elsevier
Facing the unstopped surges of COVID-19, an insufficient capacity of diagnostic testing
jeopardizes the control of disease spread. Due to a centralized setting and a long …