Application of nanotechnology in treatment of leishmaniasis: a review

M Akbari, A Oryan, G Hatam - Acta tropica, 2017 - Elsevier
Leishmaniasis is a neglected tropical disease caused by a protozoan species of the genus
Leishmania affecting mostly the develo** countries. The disease with current mortality rate …

Multi-targeting andrographolide and its natural analogs as potential therapeutic agents

V Kishore, N Sastry Yarla, A Bishayee… - Current topics in …, 2017 - ingentaconnect.com
Andrographis paniculata (A. paniculata) is a medicinal plant used in the Indian and Chinese
traditional medicinal systems for its various beneficial properties of therapeutics. This is due …

Development of high efficacy peptide coated iron oxide nanoparticles encapsulated amphotericin B drug delivery system against visceral leishmaniasis

R Kumar, K Pandey, GC Sahoo, S Das… - Materials Science and …, 2017 - Elsevier
Visceral leishmaniasis, a protozoan disease transmitted by phlebotomine sandflies which
affect mostly in Indian sub-continent. The treatment for visceral leishmaniasis (VL) caused by …

[HTML][HTML] Different susceptibilities of Leishmania spp. promastigotes to the Annona muricata acetogenins annonacinone and corossolone, and the Platymiscium …

NS Vila-Nova, SM de Morais, MJC Falcão… - Experimental …, 2013 - Elsevier
Leishmaniasis is a zoonotic disease that can manifest itself in visceral and cutaneous form.
The aim of this study was to search for new leishmanicidal compounds. Preliminarily …

Promising natural products for the treatment of cutaneous leishmaniasis: A review of in vitro and in vivo studies

RC Afonso, RMK Yien, LBO de Siqueira… - Experimental …, 2023 - Elsevier
Although there are available treatments for cutaneous leishmaniasis (CL), the drugs used
are far from ideal, toxic, and costly, in addition to the challenge faced by the development of …

Evaluating the potential of ursolic acid as bioproduct for cutaneous and visceral leishmaniasis

P Bilbao-Ramos, DR Serrano, HK Ruiz Saldaña… - Molecules, 2020 - mdpi.com
Leishmaniasis affects around 12 million people worldwide and is estimated to cause the
ninth-largest disease burden. There are three main forms of the disease, visceral (VL) …

Synthesis, characterization and antileishmanial activity of copper (II) and zinc (II) complexes with diamine ligands

CASR Condé, MV De Almeida, GS Da Silva… - Transition Metal …, 2022 - Springer
A new set of copper-and zinc-diamine (N-alkylated (L1) and N, N'-dialkylated (L2))
complexes,[Cu (L1) 2 (NO3) 2](1),[Cu (L1) 2 (Cl) 2]. 5H2O (2),[Cu (L2) 2 (NO3) 2](3),[Cu (L2) …

Combination therapy using Pentostam and Praziquantel improves lesion healing and parasite resolution in BALB/c mice co-infected with Leishmania major and …

C Khayeka–Wandabwa, HL Kutima, VCS Nyambati… - Parasites & vectors, 2013 - Springer
Background Most natural host populations are exposed to a diversity of parasite
communities and co-infection of hosts by multiple parasites is commonplace across a …

Biosynthesis, characterization and leishmanicidal activity of a biocomposite containing AgNPs-PVP-glucantime

APC Gélvez, LHS Farias, VS Pereira, ICM da Silva… - …, 2018 - Taylor & Francis
Aim: Development of functionalized nanocomposites containing AgNPs-PVP-Glucantime®
to evaluate their leishmanicidal activity as a novel method for improving the pharmacological …

Formulation of oryzalin (ORZ) liposomes: in vitro studies and in vivo fate

RM Lopes, ML Corvo, CV Eleutério… - European journal of …, 2012 - Elsevier
Oryzalin (ORZ) is a dinitroaniline that has attracted increasing interest for the treatment of
leishmaniasis. The possible use of ORZ as an antiparasitic agent is limited by low water …