Current approaches and challenges for the metabolite profiling of complex natural extracts
Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …
research. Obtaining precise information on the chemical composition of complex natural …
Metabolite induction via microorganism co-culture: a potential way to enhance chemical diversity for drug discovery
Microorganisms have a long track record as important sources of novel bioactive natural
products, particularly in the field of drug discovery. While microbes have been shown to …
products, particularly in the field of drug discovery. While microbes have been shown to …
Natural product isolation–how to get from biological material to pure compounds
F Bucar, A Wube, M Schmid - Natural product reports, 2013 - pubs.rsc.org
Covering: 2008 to 2012Since the last comprehensive review by Otto Sticher on natural
product isolation in NPR (O. Sticher, Nat. Prod. Rep., 2008, 25, 517), a plethora of new …
product isolation in NPR (O. Sticher, Nat. Prod. Rep., 2008, 25, 517), a plethora of new …
Dereplication strategies in natural product research: How many tools and methodologies behind the same concept?
The development of new drugs will certainly benefit from an ever improving knowledge of
the living beings chemistry. However, identification of drugable molecules within the …
the living beings chemistry. However, identification of drugable molecules within the …
Dereplication: racing to speed up the natural products discovery process
Covering: 1993–2014 (July) To alleviate the dereplication holdup, which is a major
bottleneck in natural products discovery, scientists have been conducting their research …
bottleneck in natural products discovery, scientists have been conducting their research …
[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II
TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - researchgate.net
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …
Concepts and methods to access novel antibiotics from actinomycetes
Actinomycetes have been proven to be an excellent source of secondary metabolites for
more than half a century. Exhibiting various bioactivities, they provide valuable approved …
more than half a century. Exhibiting various bioactivities, they provide valuable approved …
Comparative metabolite profiling and fingerprinting of medicinal licorice roots using a multiplex approach of GC–MS, LC–MS and 1D NMR techniques
Glycyrrhiza glabra, commonly known as licorice, is a popular herbal supplement used for the
treatment of chronic inflammatory conditions and possesses anticancer and antiviral …
treatment of chronic inflammatory conditions and possesses anticancer and antiviral …
Plant metabolomics: from holistic data to relevant biomarkers
Metabolomics is playing an increasingly important role in plant science. It aims at the
comprehensive analysis of the plant metabolome which consists both of primary and …
comprehensive analysis of the plant metabolome which consists both of primary and …
[PDF][PDF] Secondary metabolites of marine microbes: From natural products chemistry to chemical ecology
Marine natural products (MNPs) exhibit a wide range of pharmaceutically relevant
bioactivities, including antibiotic, antiviral, anticancer, or anti-inflammatory properties …
bioactivities, including antibiotic, antiviral, anticancer, or anti-inflammatory properties …