TRP (transient receptor potential) ion channel family: Structures, biological functions and therapeutic interventions for diseases
Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …
TRP channels
Abstract The TRP (Transient Receptor Potential) superfamily of cation channels is
remarkable in that it displays greater diversity in activation mechanisms and selectivities …
remarkable in that it displays greater diversity in activation mechanisms and selectivities …
TRP channels and pain
D Julius - Annual review of cell and developmental biology, 2013 - annualreviews.org
Nociception is the process whereby primary afferent nerve fibers of the somatosensory
system detect noxious stimuli. Pungent irritants from pepper, mint, and mustard plants have …
system detect noxious stimuli. Pungent irritants from pepper, mint, and mustard plants have …
How plants sense and respond to stressful environments
J Lamers, T Van Der Meer, C Testerink - Plant Physiology, 2020 - academic.oup.com
Plants are exposed to an ever-changing environment to which they have to adjust
accordingly. Their response is tightly regulated by complex signaling pathways that all start …
accordingly. Their response is tightly regulated by complex signaling pathways that all start …
An introduction to TRP channels
▪ Abstract The aim of this review is to provide a basic framework for understanding the
function of mammalian transient receptor potential (TRP) channels, particularly as they have …
function of mammalian transient receptor potential (TRP) channels, particularly as they have …
Heat-dependent opening of TRPV1 in the presence of capsaicin
Transient receptor potential vanilloid member 1 (TRPV1) is a Ca2+-permeable cation
channel that serves as the primary heat and capsaicin sensor in humans. Using cryo-EM, we …
channel that serves as the primary heat and capsaicin sensor in humans. Using cryo-EM, we …
The transient receptor potential family of ion channels
B Nilius, G Owsianik - Genome biology, 2011 - Springer
The transient receptor potential (TRP) multigene superfamily encodes integral membrane
proteins that function as ion channels. Members of this family are conserved in yeast …
proteins that function as ion channels. Members of this family are conserved in yeast …
Transient receptor potential cation channels in disease
The transient receptor potential (TRP) superfamily consists of a large number of cation
channels that are mostly permeable to both monovalent and divalent cations. The 28 …
channels that are mostly permeable to both monovalent and divalent cations. The 28 …
[HTML][HTML] TRP channels in thermosensation
M Kashio, M Tominaga - Current Opinion in Neurobiology, 2022 - Elsevier
The ability to sense external temperature is assumed by somatosensory neurons, in which
temperature information is converted to neural activity by afferent input to the central nervous …
temperature information is converted to neural activity by afferent input to the central nervous …
[HTML][HTML] Mammalian transient receptor potential TRPA1 channels: from structure to disease
K Talavera, JB Startek, J Alvarez-Collazo… - Physiological …, 2020 - journals.physiology.org
The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …
cation channels remarkably conserved through the animal kingdom. Mammals have only …