Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Cancer is a second leading disease-causing death worldwide that will continuously grow as
much as 70% in the next 20 years. Chemotherapy is still becoming a choice for cancer …

Osteosarcoma cancers are becoming more common in children and young adults, and
existing treatments have low efficacy and a very high mortality rate, making it pressing to …

Plants have been used as medicinal agents since the origin of mankind. High cost and
severe side effects associated with conventional chemotherapy has limited their general …

Plumbagin is one of the simplest plant secondary metabolite of three major phylogenic
families viz. Plumbaginaceae, Droseraceae, and Ebenceae, and exhibits highly potent …

Chemical investigation of many bacterial and fungal, as well as plant species has revealed
the presence of interesting compounds derived from naphthalene-1, 4-naphthoquinones …

ETHNOPHARMACOLOGICAL RELEVANCE: Ethnobotanical reports on more than 100
southern African medicinal plants with dermatological relevance have been highlighted, yet …

Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone, PLB), a naturally occurring
naphthoquinone mainly isolated from the plant Plumbago zeylanica L., has been proven to …

Plumbagin is a naphthoquinone derived yellow crystalline phytochemical. Plumbagin has a
wide range of biological effects including cytotoxicity against cancer cells both in vitro and in …

Prostate cancer (PCa) is the second leading cause of cancer-related deaths in men.
Hormone-refractory invasive PCa is the end stage and accounts for the majority of PCa …