Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles

S Dabrowska, A Andrzejewska, B Lukomska… - Journal of …, 2019 - Springer
Ischemic stroke is the third cause of death in the developed countries and the main reason
of severe disability. Brain ischemia leads to the production of damage-associated molecular …

[HTML][HTML] Stem cell therapy for abrogating stroke-induced neuroinflammation and relevant secondary cell death mechanisms

C Stonesifer, S Corey, S Ghanekar, Z Diamandis… - Progress in …, 2017 - Elsevier
Ischemic stroke is a leading cause of death worldwide. A key secondary cell death
mechanism mediating neurological damage following the initial episode of ischemic stroke …

Platelet-rich blood derivatives for stem cell-based tissue engineering and regeneration

EA Masoudi, J Ribas, G Kaushik, J Leijten… - Current stem cell …, 2016 - Springer
Platelet-rich blood derivatives have been widely used in different fields of medicine and
stem cell-based tissue engineering. They represent natural cocktails of autologous growth …

Stem cell‐based cell therapy for neuroprotection in stroke: A review

R Rikhtegar, M Yousefi, S Dolati… - Journal of cellular …, 2019 - Wiley Online Library
Neurological disorders, such as stroke, are triggered by a loss of neurons and glial cells.
Ischemic stroke remains a substantial problem for industrialized countries. Over the previous …

Platelet biology in regenerative medicine of skeletal muscle

D Scully, KM Naseem, A Matsakas - Acta Physiologica, 2018 - Wiley Online Library
Platelet‐based applications such as platelet‐rich plasma (PRP) and platelet releasate have
gained unprecedented attention in regenerative medicine across a variety of tissues as of …

Past and future of neurotrophic growth factors therapies in ALS: from single neurotrophic growth factor to stem cells and human platelet lysates

F Gouel, AS Rolland, JC Devedjian, T Burnouf… - Frontiers in …, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that typically results
in death within 3–5 years after diagnosis. To date, there is no curative treatment and …

Can the administration of platelet lysates to the brain help treat neurological disorders?

O Nebie, L Buée, D Blum, T Burnouf - Cellular and Molecular Life Sciences, 2022 - Springer
Neurodegenerative disorders of the central nervous system (CNS) and brain traumatic
insults are characterized by complex overlap** pathophysiological alterations …

Ischemic brain stroke and mesenchymal stem cells: An overview of molecular mechanisms and therapeutic potential

Y **gli, W **g, Y Saeed - Stem cells international, 2022 - Wiley Online Library
Ischemic brain injury is associated with a high rate of mortality and disability with no effective
therapeutic strategy. Recently, a growing number of studies are focusing on mesenchymal …

cPKCγ-modulated autophagy contributes to ischemic preconditioning–induced neuroprotection in mice with ischemic stroke via mTOR-ULK1 pathway

Y Zhang, L Ma, Y Yan, L Zhao, S Han, D Wu… - Translational stroke …, 2023 - Springer
Neuron-specific conventional protein kinase C (cPKC) γ mediates cerebral hypoxic
preconditioning (HPC). In parallel, autophagy plays a prosurvival role in ischemic …

Time-dependent effects of platelet-rich plasma on the memory and hippocampal synaptic plasticity impairment in vascular dementia induced by chronic cerebral …

M Bayat, S Zabihi, N Karbalaei, M Haghani - Brain research bulletin, 2020 - Elsevier
The present study aimed to investigate the effects of early and late administration of platelet-
rich plasma (PRP) on learning-memory and hippocampal synaptic plasticity impairment in …