Acute kidney injury (AKI) is a major kidney disease featured by a rapid decline of renal
function. Pathologically, AKI is characterized by tubular epithelial cell injury and death …

Acute kidney injury (AKI) is a complex condition that can occur in both community and
hospital settings and has many aetiologies. These aetiologies may be infectious, toxic …

The pathogenesis of acute kidney injury (AKI) is still not fully understood, and effective
interventions are lacking. Here, we explored whether methyltransferase 3 (METTL3) was …

SUMMARY INTRODUCTION Acute kidney injury (AKI) is a frequent event among critically ill
patients hospitalized in intensive care units (ICU) and represents a global public health …

Cold-inducible RNA-binding protein (CIRP) is a novel sepsis inflammatory mediator and
C23 is a putative CIRP competitive inhibitor. Therefore, we hypothesized that C23 can …

Pregnancy-related acute kidney injury (AKI) is a major public health problem with substantial
maternal and fetal morbidity and mortality. Women with pregnancy-related AKI require …

The kidney is vulnerable to hypoxia-induced injury. One of the mechanisms underlying this
phenomenon is cell apoptosis triggered by hypoxia-inducible factor-1-α (HIF-1α) activation …

Background There is a marked paucity of data concerning AKI in Sub-Saharan Africa, where
there is a substantial burden of trauma and HIV. Methods Prospective data was collected on …

The development of medical countermeasures against acute and delayed multi-organ injury
requires animal models predictive of the human response to radiation and its treatment. Late …

Critically ill patients who develop acute kidney injury (AKI) are more than twice as likely to
die in hospital. However, it is not clear to what extent AKI is the cause of excess mortality, or …