Detergents are widely used for membrane protein solubilization, purification, and structural
analysis. Over the past two decades, much effort has been made to design novel detergents …

The first member and eponym of the rhodopsin family was identified in the 1930s as the
visual pigment of the rod photoreceptor cell in the animal retina. It was found to be a …

Viruses with membranes fuse them with cellular membranes, to transfer their genomes into
cells at the beginning of infection. For Influenza virus, the membrane glycoprotein involved …

While most nanoproteomics approaches for the analysis of low‐input samples are based on
bottom‐up proteomics workflows, top‐down approaches enabling proteoform …

Extracting membrane proteins from the hydrophobic environment of the biological
membrane, in a physiologically relevant and stable state, suitable for downstream analysis …

The field of chemical senses has made major progress in understanding the cellular
mechanisms of olfaction and taste in the past 2 decades. However, the molecular …

Structural studies of integral membrane proteins have been limited by the intrinsic
conformational flexibility and the need to stabilize the proteins in solution. Stabilization by …

Membrane proteins are of biological and pharmaceutical significance. However, their
structural study is extremely challenging mainly due to the fact that only a small number of …

Detergents are essential tools for functional and structural studies of membrane proteins.
However, conventional detergents are limited in their scope and utility, particularly for …

Membrane proteins play essential roles in a number of biological processes, and their
structures are important in elucidating such processes at the molecular level and also for …