Alkenes and their derivatives are featured widely in a variety of natural products,
pharmaceuticals, and advanced materials. Significant efforts have been made toward the …

Conspectus Harnessing biocatalysts for novel abiological transformations is a longstanding
goal of synthetic chemistry. Combining the merits of biocatalysis and photocatalysis allows …

Plastics play an essential role in modern society; however, the relentless growth of their
production is threatening both human health and ecosystems. As a result, there are …

In nature, coenzyme-independent oxidases have evolved in selective catalysis using
isolated substrate-binding pockets. Single-atom nanozymes (SAzymes), an emerging type of …

Proteins are nature's primary building blocks for the construction of sophisticated molecular
machines and dynamic materials, ranging from protein complexes such as photosystem II …

Late-stage functionalization (LSF) introduces functional group or structural modification at
the final stage of the synthesis of natural products, drugs, and complex compounds. It is …

Metalloenzymes catalyze a variety of reactions using a limited number of natural amino
acids and metallocofactors. Therefore, the environment beyond the primary coordination …

The efficiency, selectivity and sustainability benefits offered by enzymes are enticing
chemists to consider biocatalytic transformations to complement or even supplant more …

The engineering of catalysts with desirable properties can be accelerated by computer-
aided design. To achieve this aim, features of molecular catalysts can be condensed into …

Biocatalysis, using defined enzymes for organic transformations, has become a common
tool in organic synthesis, which is also frequently applied in industry. The generally high …