Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

The naked mole‐rat (Heterocephalus glaber) has fascinated zoologists for at least half a
century. It has also generated considerable biomedical interest not only because of its …

Naked mole-rats (NMRs, Heterocephalus glaber) are the longest-lived rodents with a
maximum life span exceeding 37 years. They exhibit a delayed aging phenotype and …

Develo** a universal representation of cells which encompasses the tremendous
molecular diversity of cell types within the human body and more generally, across species …

The naked mole-rat (Heterocephalus glaber) is a long-lived rodent species showing
resistance to the development of cancer. Although naked mole-rats have been reported to …

Naked mole-rats (NMRs) are best known for their extreme longevity and cancer resistance,
suggesting that their immune system might have evolved to facilitate these phenotypes …

The nuclear factor-κB (NF-κB) signaling pathway is one of the most well-studied pathways
related to inflammation, and its involvement in aging has attracted considerable attention. As …

Driven by co‐evolution with pathogens, host immunity continuously adapts to optimize
defence against pathogens within a given environment. Recent advances in genetics …

Although tumor‐specific neoantigen‐based cancer vaccines hold tremendous potential, it
still faces low cross‐presentation associated with severe degradation via endocytosis …

Lifespan varies significantly among mammals, with more than 100‐fold difference between
the shortest and longest living species. This natural difference may uncover the evolutionary …