Advances in nanomedicine have become indispensable for targeted drug delivery, early
detection, and increasingly personalized approaches to cancer treatment. Nanoparticle …

Cancer cells have characteristics of acquired and intrinsic resistances to chemotherapy
treatment—due to the hostile tumor microenvironment—that create a significant challenge …

Post-resection recurrence remains an intractable problem in hepatocellular carcinoma
(HCC) management. Natural killer (NK) cell infusion is considered as a promising cancer …

Cancer has become the primary reason for industrial countries death. Although first-line
treatments have achieved remarkable results in inhibiting tumors, they could have serious …

The pH (low) insertion peptides (pHLIPs) target acidity at the surfaces of cancer cells and
show utility in a wide range of applications, including tumor imaging and intracellular …

Since their invention in 1991, peptide nucleic acids (PNAs) have been used in a myriad of
chemical and biological assays. More recently, peptide nucleic acids have also been …

Acidity is a biomarker of cancer that is not subject to the blunting clonal selection effects that
reduce the efficacy of other biomarker technologies, such as antibody targeting. The pH …

Thousands of patients die each year from residual cancer that remains following
cytoreductive surgery. Use of tumor-targeted fluorescent dyes (TTFDs) to illuminate …

Fluorescent dye labeling is a common strategy to analyze the fate of administered
nanoparticles in living organisms. However, to which extent the labeling processes can alter …

Acidosis of the tumor microenvironment is a hallmark of tumor progression and has emerged
as an essential biomarker for cancer diagnosis, prognosis, and evaluation of treatment …