The role of microbiome in brain development and neurodegenerative diseases

V Nandwana, NK Nandwana, Y Das, M Saito, T Panda… - Molecules, 2022 - mdpi.com
Hundreds of billions of commensal microorganisms live in and on our bodies, most of which
colonize the gut shortly after birth and stay there for the rest of our lives. In animal models …

Role of nanomedicine-based therapeutics in the treatment of CNS disorders

ZH Guo, S Khattak, MA Rauf, MA Ansari, MN Alomary… - Molecules, 2023 - mdpi.com
Central nervous system disorders, especially neurodegenerative diseases, are a public
health priority and demand a strong scientific response. Various therapy procedures have …

Boron-containing compounds on neurons: Actions and potential applications for treating neurodegenerative diseases

M Barrón-González, AV Montes-Aparicio… - Journal of inorganic …, 2023 - Elsevier
Boron-containing compounds (BCC) exert effects on neurons. After the expanding of both
the identification and synthesis of new BCC, novel effects in living systems have been …

Boron: An intriguing factor in retarding Alzheimer's progression

A Das, V Rajput, D Chowdhury, R Choudhary… - Neurochemistry …, 2024 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that is the fifth most common
cause of mortality worldwide and the second most common cause of death in developed …

Effects of hydroxyl group, glycosylation and solvents on the antioxidant activity and mechanism of maclurin and its derivatives: Theoretical insights

Y Xue, M Chen, Z Li, L Zhang, G Wang, Y Zheng… - Journal of Molecular …, 2022 - Elsevier
Maclurin (MAC) and its derivatives received increasing interest due to their diverse
biological activities. However, understanding of their antioxidant properties remains …

Effects of Boron on Learning and Behavioral Disorders in Rat Autism Model Induced by Intracerebroventricular Propionic Acid

NA Alacabey, D Coşkun, A Ateşşahin - Biological trace element research, 2024 - Springer
Autism spectrum disorder is a neurodevelopmental disorder in which learning,
communication, and social interaction are impaired. Research has sought to minimize the …

Synthesis, in silico, and biological evaluation of a borinic tryptophan-derivative that induces melatonin-like amelioration of cognitive deficit in male rat

M Barrón-González, MC Rosales-Hernández… - International Journal of …, 2022 - mdpi.com
Preclinical and clinical evidence supports melatonin and its analogues as potential
treatment for diseases involving cognitive deficit such as Alzheimer's disease. In this work …

Identification and evaluation of boronic compounds ameliorating cognitive deficit in orchiectomized rats

ED Farfán-García, MC Rosales-Hernández… - Journal of Trace …, 2022 - Elsevier
Background Boron is a trace element with increasing importance in drug design. In this
sense, boronic acids are emerging as therapeutic agents for several diseases. Methods …

The Cracked Potential of Boron-containing Compounds in Alzheimer's Disease

MA Soriano-Ursúa… - Central Nervous System …, 2023 - ingentaconnect.com
Alzheimer's disease (AD) is a relevant neurodegenerative disease worldwide. Its relevancy
is mainly due to its high prevalence and high global burden. Metalloids have attracted …

Borolatonin limits cognitive deficit and neuron loss while increasing proBDNF in ovariectomised rats

M Barrón‐González, AM Rivera‐Antonio… - Fundamental & …, 2024 - Wiley Online Library
Background Borolatonin is a potential therapeutic agent for some neuronal diseases such
as Alzheimer's disease (AD). Its administration exerts ameliorative effects such as those …