Leptin, the protein product of the obese (ob or Lep) gene, is a hormone synthesized by
adipocytes that signals available energy reserves to the brain, and thereby influences …

To achieve energy balance and maintain a constant BW, changes in feed intake and energy
expenditure must be coordinated and tightly regulated. This may not hold true for some …

Lipid storage is an evolutionary conserved process that exists in all organisms from simple
prokaryotes to humans. In Metazoa, long-term lipid accumulation is restricted to specialized …

The production of peptide hormones by skeletal muscle tissue is a promising area of gene
therapy. Skeletal muscle myogenesis can be induced in vitro, resulting in the fusion of …

Leptin is an adipocyte-derived hormone/cytokine that links nutritional status with
neuroendocrine and immune functions. Initially described as an anti-obesity hormone, leptin …

Leptin is a key factor for the regulation of food intake and energy homeostasis in mammals,
but information regarding its role in teleosts is still limited. There are large differences …

The present study reports the complete coding sequences for two paralogues for leptin
(sLepA1 and sLepA2) and leptin receptor (sLepR) in Atlantic salmon. The deduced 171 …

The neuroendocrinology of ingestive behavior is a topic central to human health, particularly
in light of the prevalence of obesity, eating disorders, and diabetes. The study of food intake …

It has now become accepted that the immune system and neuroendocrine system form an
integrated part of our physiology. Immunological defense mechanisms act in concert with …

More than 20 years after characterization of the key regulator of mammalian energy balance,
leptin, we identified the leptin (LEP) genes of chicken (Gallus gallus) and duck (Anas …