The immune system plays a vital role in suppressing tumor cell progression. The tumor
microenvironment augmented with significant levels of tumor-infiltrating lymphocytes has …

Understanding tumor progression and carcinogenesis requires a detailed study of proteins
that play a significant role in the regulation of pathways and processes. Proteins are the …

The CDKs are known to play a critical role in cell cycle regulation process. Among the
different groups of CDKs, CDK4 overexpression/hyperactivation is found to be present in …

Breast cancer represents the leading cause of mortality among women worldwide. Since the
complexity of breast cancer as a disease resides in its heterogeneity as it consists of several …

Breast cancer is the primary factor contributing to female mortality worldwide. The incidence
has overtaken lung cancer. It is the most difficult illness due to its heterogeneity and is made …

Breast cancer is the leading cause of mortality among women worldwide. Being a
heterogenous disease it comprises many different subtypes that differ in their pathological …

Breast cancer (BC) is the most common type of malignancy globally and the main reason
why women die from tumours. The Warburg effect, a characteristic of tumor, describes how …

Role of Tumor Microenvironment in Breast Cancer and Targeted Therapies discusses the
current understanding of breast cancer tumor microenvironment components, their role in …

Breast carcinoma is the leading factor in women's cancer-related fatalities. Due to its
numerous inherent molecular subtypes, breast cancer is an extremely diverse illness. The …

CDKs require modulatory subunits to bind them, known as cyclins, to exert their effects. The
latter are formed and destroyed at various cell cycle stages in a specific and timely manner …