Renal ischemia-reperfusion (IR) contributes to the development of ischemic acute renal
failure (ARF). Multi-factorial processes are involved in the development and progression of …

Cellular metabolic changes during chronic kidney disease (CKD) may induce higher
production of oxygen radicals that play a significant role in the progression of renal damage …

There is increasing evidence to suggest that toxic oxygen radicals play an essential role in
the pathogenesis of ischemia/reperfusion (I/R) injury in the kidney. This study was designed …

BACKGROUND: Oxygen free radicals are important components involved in the
pathophysiological processes observed during ischemia/reperfusion (I/R). OBJECTIVE: This …

Objective (s): Ischemia/reperfusion (I/R) is the leading cause of acute kidney injury. This
study aimed to elucidate the reno-protective effect of gamma-oryzanol (GO) by comparing …

The pathophysiological process of ischemia and reperfusion injury (IRI), an inevitable step
in organ transplantation, causes important biochemical and structural changes that can …

Epidemiological studies have shown that male sex is an independent risk factor for the
development and progression of renal disease, and men progress to end stage renal …

This study investigated the protective effects of carvedilol, a potent antioxidant, in a rat model
of tourniquet-induced ischaemia-reperfusion injury of the hind limb. Thirty rats were divided …

Background: Although doxorubicin (DXR) is one of the most used anticancer drugs, it can
cause life-threatening renal damage. There has been no effective treatment for DXR …

This study investigated the protective effects of carvedilol alone and coadministered with
prednisolone and diltiazem on doxorubicin (DOX) and 5‐fluorouracil (5‐FU)‐induced …