Circulating tumor cell isolation for cancer diagnosis and prognosis

Z Deng, S Wu, Y Wang, D Shi - EBioMedicine, 2022‏ - thelancet.com
Circulating tumor cells (CTCs) are tumor cells that shed from the primary tumor and
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …

Aptamers 101: aptamer discovery and in vitro applications in biosensors and separations

LF Yang, M Ling, N Kacherovsky, SH Pun - Chemical science, 2023‏ - pubs.rsc.org
Aptamers are single-stranded nucleic acids that bind and recognize targets much like
antibodies. Recently, aptamers have garnered increased interest due to their unique …

Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021‏ - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment

S Qi, N Duan, IM Khan, X Dong, Y Zhang, S Wu… - Biotechnology …, 2022‏ - Elsevier
Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …

Recent development in rapid detection techniques for microorganism activities in food matrices using bio-recognition: A review

H Jayan, H Pu, DW Sun - Trends in Food Science & Technology, 2020‏ - Elsevier
Background Microbial contamination is an increasing concern in the food industry. In order
to understand the effect of microorganisms, the study of their characteristics and behavior in …

[HTML][HTML] Recent progress in aptamer-based microfluidics for the detection of circulating tumor cells and extracellular vesicles

D Sun, Y Ma, M Wu, Z Chen, L Zhang, J Lu - Journal of Pharmaceutical …, 2023‏ - Elsevier
Liquid biopsy is a technology that exhibits potential to detect cancer early, monitor therapies,
and predict cancer prognosis due to its unique characteristics, including noninvasive …

DNA‐based nanomaterials for analysis of extracellular vesicles

J Deng, C Liu, J Sun - Advanced Materials, 2024‏ - Wiley Online Library
Extracellular vesicles (EVs) are cell‐derived nanovesicles comprising a myriad of molecular
cargo such as proteins and nucleic acids, playing essential roles in intercellular …

Microfluidic nanomaterials: From synthesis to biomedical applications

K Illath, S Kar, P Gupta, A Shinde, S Wankhar… - Biomaterials, 2022‏ - Elsevier
Microfluidic platforms gain popularity in biomedical research due to their attractive inherent
features, especially in nanomaterials synthesis. This review critically evaluates the current …

[HTML][HTML] EMT-associated heterogeneity in circulating tumor cells: sticky friends on the road to metastasis

A Genna, AM Vanwynsberghe, AV Villard, C Pottier… - Cancers, 2020‏ - mdpi.com
Epithelial–mesenchymal transitions (EMTs) generate hybrid phenotypes with an enhanced
ability to adapt to diverse microenvironments encountered during the metastatic spread …

Microfluidic systems for particle capture and release: A review

L Gong, A Cretella, Y Lin - Biosensors and Bioelectronics, 2023‏ - Elsevier
Microfluidic technology has emerged as a promising tool in various applications, including
biosensing, disease diagnosis, and environmental monitoring. One of the notable features of …