[HTML][HTML] An overview of bioinformatics tools for epitope prediction: implications on vaccine development

RE Soria-Guerra, R Nieto-Gomez… - Journal of biomedical …, 2015 - Elsevier
Exploitation of recombinant DNA and sequencing technologies has led to a new concept in
vaccination in which isolated epitopes, capable of stimulating a specific immune response …

Systems vaccinology

B Pulendran, S Li, HI Nakaya - Immunity, 2010 - cell.com
Vaccination is one of the greatest triumphs of modern medicine, yet we remain largely
ignorant of the mechanisms by which successful vaccines stimulate protective immunity …

Multiepitope-based subunit vaccine design and evaluation against respiratory syncytial virus using reverse vaccinology approach

M Tahir ul Qamar, Z Shokat, I Muneer, UA Ashfaq… - Vaccines, 2020 - mdpi.com
Respiratory syncytial virus (RSV) is primarily associated with respiratory disorders globally.
Despite the availability of information, there is still no competitive vaccine available for RSV …

Current progress of immunoinformatics approach harnessed for cellular-and antibody-dependent vaccine design

A Kazi, C Chuah, ABA Majeed, CH Leow… - Pathogens and global …, 2018 - Taylor & Francis
Immunoinformatics plays a pivotal role in vaccine design, immunodiagnostic development,
and antibody production. In the past, antibody design and vaccine development depended …

Immunoinformatics: an integrated scenario

N Tomar, RK De - Immunology, 2010 - Wiley Online Library
Genome sequencing of humans and other organisms has led to the accumulation of huge
amounts of data, which include immunologically relevant data. A large volume of clinical …

An overview of progress from empirical to rational design in modern vaccine development, with an emphasis on computational tools and immunoinformatics …

S Soleymani, A Tavassoli, MR Housaindokht - Computers in biology and …, 2022 - Elsevier
Vaccination remains the most effective strategy for preventing and controlling infectious
diseases. Numerous conventional vaccines, especially live attenuated, inactivated (killed) …

Designing of multi-epitope chimeric vaccine using immunoinformatic platform by targeting oncogenic strain HPV 16 and 18 against cervical cancer

A Kumar, U Sahu, P Kumari, A Dixit, P Khare - Scientific Reports, 2022 - nature.com
Cervical cancer is the most common gynaecological cancer and reaches an alarming stage.
HPVs are considered the main causative agents for cervical cancer and other sexually …

Rational design of multi epitope-based subunit vaccine by exploring MERS-COV proteome: Reverse vaccinology and molecular docking approach

UA Ashfaq, S Saleem, MS Masoud, M Ahmad… - PLoS …, 2021 - journals.plos.org
Middle East respiratory syndrome (MERS-COV), first identified in Saudi Arabia, was caused
by a novel strain of coronavirus. Outbreaks were recorded from different regions of the world …

Insight into the current Toxoplasma gondii DNA vaccine: a review article

X Zhang, H Yuan, YS Mahmmod, Z Yang… - Expert Review of …, 2023 - Taylor & Francis
Introduction Toxoplasma gondii (T. gondii) is a widespread protozoan with significant
economic losses and public health importance. But so far, the protective effect of reported …

Immunoinformatics: a brief review

N Tomar, RK De - Immunoinformatics, 2014 - Springer
A large volume of data relevant to immunology research has accumulated due to
sequencing of genomes of the human and other model organisms. At the same time, huge …