Tumor-associated microglia and macrophages in glioblastoma: From basic insights to therapeutic opportunities
G Wang, K Zhong, Z Wang, Z Zhang, X Tang… - Frontiers in …, 2022 - frontiersin.org
Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults.
Currently, the standard treatment of glioblastoma includes surgery, radiotherapy, and …
Currently, the standard treatment of glioblastoma includes surgery, radiotherapy, and …
The brain tumor microenvironment
High‐grade brain tumors are heterogeneous with respect to the composition of bona fide
tumors cells and with respect to a range of intermingling parenchymal cells. Glioblastomas …
tumors cells and with respect to a range of intermingling parenchymal cells. Glioblastomas …
Engineered macrophage-membrane-coated nanoparticles with enhanced PD-1 expression induce immunomodulation for a synergistic and targeted antiglioblastoma …
T Yin, Q Fan, F Hu, X Ma, Y Yin, B Wang, L Kuang… - Nano …, 2022 - ACS Publications
Glioblastoma (GBM), the most common subtype of malignant gliomas, is characterized by
aggressive infiltration, high malignancy, and poor prognosis. The frustrating anti-GBM …
aggressive infiltration, high malignancy, and poor prognosis. The frustrating anti-GBM …
Tumor-associated microglia and macrophages in the glioblastoma microenvironment and their implications for therapy
Simple Summary Patients with glioblastoma—the most frequent and malignant primary brain
tumor—have a poor prognosis with a median survival of less than 15 months. Despite …
tumor—have a poor prognosis with a median survival of less than 15 months. Despite …
The brain tumor microenvironment
High‐grade brain tumors are heterogeneous with respect to the composition of bona fide
tumor cells and with respect to a range of intermingling parenchymal cells. Glioblastomas …
tumor cells and with respect to a range of intermingling parenchymal cells. Glioblastomas …
[HTML][HTML] Immune microenvironment of gliomas
A Gieryng, D Pszczolkowska, KA Walentynowicz… - Laboratory …, 2017 - Elsevier
High-grade gliomas are rapidly progressing tumors of the central nervous system (CNS) with
a very poor prognosis despite extensive resection combined with radiation and/or …
a very poor prognosis despite extensive resection combined with radiation and/or …
Immune evasion strategies of glioblastoma
Glioblastoma (GBM) is the most devastating brain tumor, with associated poor prognosis.
Despite advances in surgery and chemoradiation, the survival of afflicted patients has not …
Despite advances in surgery and chemoradiation, the survival of afflicted patients has not …
The molecular profile of microglia under the influence of glioma
W Li, MB Graeber - Neuro-oncology, 2012 - academic.oup.com
Microglia, which contribute substantially to the tumor mass of glioblastoma, have been
shown to play an important role in glioma growth and invasion. While a large number of …
shown to play an important role in glioma growth and invasion. While a large number of …
Tumor‐associated macrophages exhibit pro‐and anti‐inflammatory properties by which they impact on pancreatic tumorigenesis
O Helm, J Held‐Feindt… - … journal of cancer, 2014 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) still ranking 4th in the order of fatal tumor
diseases is characterized by a profound tumor stroma with high numbers of tumor …
diseases is characterized by a profound tumor stroma with high numbers of tumor …
Glioblastoma-associated microglia and macrophages: targets for therapies to improve prognosis
CC Poon, S Sarkar, VW Yong, JJP Kelly - Brain, 2017 - academic.oup.com
Glioblastoma is the most common and most malignant primary adult human brain tumour.
Diagnosis of glioblastoma carries a dismal prognosis. Treatment resistance and tumour …
Diagnosis of glioblastoma carries a dismal prognosis. Treatment resistance and tumour …