Fear memory

I Izquierdo, CRG Furini, JC Myskiw - Physiological reviews, 2016 - journals.physiology.org
Fear memory is the best-studied form of memory. It was thoroughly investigated in the past
60 years mostly using two classical conditioning procedures (contextual fear conditioning …

Nicotinic ACh receptors as therapeutic targets in CNS disorders

KT Dineley, AA Pandya, JL Yakel - Trends in pharmacological sciences, 2015 - cell.com
The neurotransmitter acetylcholine (ACh) can regulate neuronal excitability by acting on the
cys-loop cation-conducting ligand-gated nicotinic ACh receptor (nAChR) channels. These …

Kaempferol as a therapeutic agent in Alzheimer's disease: Evidence from preclinical studies

X Dong, S Zhou, J Nao - Ageing research reviews, 2023 - Elsevier
Background Alzheimer's disease (AD) is the most common type of dementia and seriously
affects human life and health. Kaempferol (KMP) is a common flavonoid, that is mainly …

[HTML][HTML] The impact of neurotransmitters on the neurobiology of neurodegenerative diseases

SE Davis, AB Cirincione, AC Jimenez-Torres… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases affect millions of people worldwide. Neurodegenerative
diseases result from progressive damage to nerve cells in the brain or peripheral nervous …

Cholinergic circuits in cognitive flexibility

VF Prado, H Janickova, MA Al-Onaizi, MAM Prado - Neuroscience, 2017 - Elsevier
Cognitive flexibility, the ability to adjust behavior in response to new and unexpected
conditions in the environment, is essential for adaptation to new challenges and survival …

Acetylcholine signaling system in progression of lung cancers

JR Friedman, SD Richbart, JC Merritt, KC Brown… - Pharmacology & …, 2019 - Elsevier
The neurotransmitter acetylcholine (ACh) acts as an autocrine growth factor for human lung
cancer. Several lines of evidence show that lung cancer cells express all of the proteins …

Application of graphite screen printed electrode modified with dysprosium tungstate nanoparticles in voltammetric determination of epinephrine in the presence of …

H Beitollahi, Z Dourandish, S Tajik, MR Ganjali… - Journal of Rare …, 2018 - Elsevier
The current work focuses on the development of a sensitive and selective electrochemical
device based on a graphite screen printed electrode modified with Dy 2 (WO 4) 3 …

Structural bioinformatics studies of serotonin, dopamine and norepinephrine transporters and their AlphaFold2 predicted water-soluble QTY variants and uncovering …

T Karagöl, A Karagöl, S Zhang - PloS one, 2024 - journals.plos.org
Monoamine transporters including transporters for serotonin, dopamine, and norepinephrine
play key roles in monoaminergic synaptic signaling, involving in the molecular etiology of a …

ChAT–ChR2–EYFP mice have enhanced motor endurance but show deficits in attention and several additional cognitive domains

B Kolisnyk, MS Guzman, S Raulic, J Fan… - Journal of …, 2013 - jneurosci.org
Acetylcholine (ACh) is an important neuromodulator in the nervous system implicated in
many forms of cognitive and motor processing. Recent studies have used bacterial artificial …

Acute lung injury is reduced by the α7nAChR agonist PNU‐282987 through changes in the macrophage profile

NM Pinheiro, FPR Santana, RR Almeida… - The FASEB …, 2017 - Wiley Online Library
Nicotinic α‐7 acetylcholine receptor (nAChRα7) is a critical regulator of cholinergic anti‐
inflammatory actions in several diseases, including acute respiratory distress syndrome …