Compositional dynamics of the milk fat globule and its role in infant development

H Lee, E Padhi, Y Hasegawa, J Larke, M Parenti… - Frontiers in …, 2018 - frontiersin.org
Human milk is uniquely optimized for the needs of the develo** infant. Its composition is
complex and dynamic, driven primarily by maternal genetics, and to a lesser extent by diet …

[HTML][HTML] Milk-derived extracellular vesicles in inter-organism, cross-species communication and drug delivery

R Sanwlani, P Fonseka, SV Chitti, S Mathivanan - Proteomes, 2020 - mdpi.com
Milk is considered as more than a source of nutrition for infants and is a vector involved in
the transfer of bioactive compounds and cells. Milk contains abundant quantities of …

Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis

R Li, Y Wang, X Zhang, M Feng, J Ma, J Li, X Yang… - Molecular cancer, 2019 - Springer
Background Lysyl oxidase-like 4 (LOXL4) has been found to be dysregulated in several
human malignancies, including hepatocellular carcinoma (HCC). However, the role of …

Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth

M Samuel, D Chisanga, M Liem, S Keerthikumar… - Scientific reports, 2017 - nature.com
Exosomes are extracellular vesicles secreted by multiple cell types into the extracellular
space. They contain cell-state specific cargos which often reflects the (patho) physiological …

Mass-spectrometry-based molecular characterization of extracellular vesicles: lipidomics and proteomics

S Kreimer, AM Belov, I Ghiran, SK Murthy… - Journal of proteome …, 2015 - ACS Publications
This review discusses extracellular vesicles (EVs), which are submicron-scale, anuclear,
phospholipid bilayer membrane enclosed vesicles that contain lipids, metabolites, proteins …

The potential of exosomes from cow milk for oral delivery

JL Betker, BM Angle, MW Graner… - Journal of pharmaceutical …, 2019 - Elsevier
Many pharmaceuticals must be administered intravenously due to their poor oral
bioavailability. In addition to issues associated with sterility and inconvenience, the cost of …

MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection

J Sun, K Aswath, SG Schroeder, JD Lippolis… - BMC genomics, 2015 - Springer
Background Milk exosomes are a rich source of microRNAs (miRNAs) that are protected
from degradation. Ingestion of milk and subsequent absorption of miRNAs into recipient …

Milk exosomes: next-generation agents for delivery of anticancer drugs and therapeutic nucleic acids

AM Timofeeva, AP Paramonik, SS Sedykh… - International journal of …, 2023 - mdpi.com
Exosomes are nanovesicles 40–120 nm in diameter secreted by almost all cell types and
providing humoral intercellular interactions. Given the natural origin and high …

Role of extracellular vesicles in cell death and inflammation

R Sanwlani, L Gangoda - Cells, 2021 - mdpi.com
Extracellular vesicles (EVs) have been identified as novel mediators of intercellular
communication. They work via delivering the sequestered cargo to cells in the close vicinity …

[HTML][HTML] Milk exosomes: perspective agents for anticancer drug delivery

S Sedykh, A Kuleshova, G Nevinsky - International journal of molecular …, 2020 - mdpi.com
Exosomes are biological nanovesicles that participate in intercellular communication by
transferring biologically active chemical compounds (proteins, microRNA, mRNA, DNA, and …