The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

Gene therapy is manipulation in/of gene expression in specific cells/tissue to treat diseases.
This manipulation is carried out by introducing exogenous nucleic acids, such as DNA or …

Nanocarriers have therapeutic potential to facilitate drug delivery, including biological
agents, small-molecule drugs, and nucleic acids. However, their efficiency is limited by …

Cancer treatment still faces a lot of obstacles such as tumor heterogeneity, drug resistance
and systemic toxicities. Beyond the traditional treatment modalities, exploitation of RNA …

Nucleic acid (NA) therapeutics are a rapidly growing class of biomedicines with the ability to
manipulate gene expression in potent and specific manner, and with the enormous potential …

The ability to manipulate the size and surface properties of nanomaterials makes them a
promising vector for improving drug delivery and efficacy. Inhalation is a desirable route of …

Nanoparticle based imaging agents (NIAs) have been intensively explored in bench studies.
Unfortunately, only a few cases have made their ways to clinical translation. In this review …

Probes that exploit Förster resonance energy transfer (FRET) in their feedback mechanism
are touted for their sensitivity, robustness, and low background, and thanks to the …

Gene therapy represents a potential efficient approach of disease prevention and therapy.
However, due to their poor in vivo stability, gene molecules need to be associated with …

Quercetin (Qe) plays an important role in inflammation, antibacterial, anticancer, and aging.
However, Qe has extremely low water solubility, which is a major challenge in drug …