Lipid‐based nanoparticles have emerged as a clinically viable platform technology to
deliver nucleic acids for a wide range of healthcare applications. Within this scope, one of …

Biological membranes and membrane proteins, responsible for numerous exciting
biological processes, present one of the paramount challenges in biophysics today …

The native environment of membrane proteins is complex and scientists have felt the need
to simplify it to reduce the number of varying parameters. However, experimental problems …

Several complementary physical techniques have been used to characterize the aggregate
structures formed in solutions containing dimyristoylphosphatidylcholine (DMPC) …

This review covers current trends in studies of membrane amphiphiles and membrane
proteins using both fast tumbling bicelles and magnetically aligned bicelle media for both …

Bicelles are an attractive membrane mimetic system because of their planar surface and
lipid composition, which resemble biological membranes. In addition, their orientation and …

► Lipid bicelles have matured to full membership in the club of lipid phases.► Numerous
techniques have elucidated the character traits of bicelles.► Bicelles are exemplary citizens …

Islet amyloid polypeptide (IAPP) is an unstructured polypeptide hormone that is cosecreted
with insulin. In patients with type 2 diabetes, IAPP undergoes a transition from its natively …

Crystallization of membrane proteins remains a significant challenge. For proteins resistant
to the traditional approach of directly crystallizing from detergents, lipidic phase …

Roughly one-third of all proteins reside in biological membranes [1, 2]. Integral membrane
proteins (IMPs), which can only be released from the membrane by disruption of the …