The optimal treatment for complex fractures and large bone defects is an important unsolved
issue in orthopedics and related specialties. Approximately 5–10% of fractures fail to heal …

Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have
shown the therapeutic potential effect of MSC or their derived products. However, the …

Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …

Various diseases and toxic factors easily impair cellular and organic functions in mammals.
Organ transplantation is used to rescue organ function, but is limited by scarce resources …

The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the
early paradigm of cell replacement and differentiation as a therapeutic mechanism of action …

Mesenchymal stromal/stem cells (MSCs) are multipotent adult stem cells that support
homeostasis during tissue regeneration. In the last decade, cell therapies based on the use …

Mesenchymal stem cells (MSCs) have been widely used for tissue repair and regeneration.
However, the inherent drawbacks, including limited cell survival after cell transplantation …

Background: Treatment of large bone defects represents a major clinical problem worldwide.
Suitable bone substitute materials are commonly required to achieve successful bone …

Bone implants for clinical application should be endowed with antibacterial activity,
biocompatibility, and even osteogenesis-promoting properties. In this work, metal–organic …

Mesenchymal stem cells (MSCs) emerged as a promising therapeutic tool targeting a variety
of inflammatory disorders due to their multiple remarkable properties, such as superior …