Ions surround nucleic acids in what is referred to as an ion atmosphere. As a result, the
folding and dynamics of RNA and DNA and their complexes with proteins and with each …

In addition to continuous rapid progress in RNA structure determination, probing, and
biophysical studies, the past decade has seen remarkable advances in the development of …

The structure of ribonucleic acid (RNA) polymers is strongly dependent on the presence of,
in particular Mg2+ cations to stabilize structural features. Only in high-resolution X-ray …

The ubiquitous presence of magnesium ions in RNA has long been recognized as a key
factor governing RNA folding, and is crucial for many diverse functions of RNA molecules. In …

Motivation RNA molecules become attractive small molecule drug targets to treat disease in
recent years. Computer-aided drug design can be facilitated by detecting the RNA sites that …

RNA molecules have recently become attractive as potential drug targets due to the
increased awareness of their importance in key biological processes. The increase of the …

RNA-small molecule binding is a key regulatory mechanism which can stabilize 3D
structures and activate molecular functions. The discovery of RNA-targeting compounds is …

The gas-phase conformations of protonated 2′-deoxyadenosine,[dAdo+ H]+, and its RNA
analogue protonated adenosine,[Ado+ H]+, generated upon electrospray ionization are …

Riboswitches, which are located within certain noncoding RNA region perform functions as
genetic “switches”, regulating when and where genes are expressed in response to certain …

Metal ion is an indispensable factor for the proper folding, structural stability and functioning
of RNA molecules. However, it is very difficult for experimental methods to detect them in …