Status epilepticus (SE) treatment strategies vary substantially from one institution to another
due to the lack of data to support one treatment over another. To provide guidance for the …

Refractory status epilepticus (RSE) is defined as status epilepticus that continues despite
treatment with benzodiazepines and one antiepileptic drug. RSE should be treated promptly …

Background Phenytoin is the current standard of care for second-line treatment of paediatric
convulsive status epilepticus after failure of first-line benzodiazepines, but is only effective in …

The objective of the current article was to review the literature and discuss the degree of
evidence for various treatment strategies for status epilepticus (SE) in adults. We searched …

Purpose Systematic evaluation of published evidence-base of the efficacy of five
antiepileptic drugs–lacosamide, levetiracetam, valproate, phenytoin and phenobarbital–in …

Epilepsy is a common chronic disorder that requires long-term antiepileptic drug therapy.
Approximately one half of patients fail the initial antiepileptic drug and about 35% are …

Summary Purpose: Phenytoin (PHT), valproic acid (VPA), or levetiracetam (LEV) are
commonly used as second‐line treatment of status epilepticus (SE), but comparative studies …

For the management of status epilepticus (SE), lorazepam (LOR) is recommended as the
first and phenytoin or fosphenytoin as the second choice. Both these drugs have significant …

In recent years, there has been considerable interest in determining the function of synaptic
vesicle protein 2A and its role as a target for antiepileptic drugs. Although it is known that …

Objective This study was conducted to compare the efficacy of phenytoin, valproate and
levetiracetam in patients with GCSE. Methods This randomised controlled prospective study …