The evolving erythrocyte: red blood cells as modulators of innate immunity

HL Anderson, IE Brodsky… - The Journal of …, 2018 - journals.aai.org
The field of red cell biology is undergoing a quiet revolution. Long assumed to be inert
oxygen carriers, RBCs are emerging as important modulators of the innate immune …

The nuclear-to-cytoplasmic ratio: coupling DNA content to cell size, cell cycle, and biosynthetic capacity

S Balachandra, S Sarkar… - Annual review of genetics, 2022 - annualreviews.org
Though cell size varies between different cells and across species, the nuclear-to-
cytoplasmic (N/C) ratio is largely maintained across species and within cell types. A cell …

Transposons, genome size, and evolutionary insights in animals

A Canapa, M Barucca, MA Biscotti, M Forconi… - … and genome research, 2015 - karger.com
The relationship between genome size and the percentage of transposons in 161 animal
species evidenced that variations in genome size are linked to the amplification or the …

LTR retrotransposons contribute to genomic gigantism in plethodontid salamanders

C Sun, DB Shepard, RA Chong… - Genome biology and …, 2012 - academic.oup.com
Among vertebrates, most of the largest genomes are found within the salamanders, a clade
of amphibians that includes 613 species. Salamander genome sizes range from∼ 14 to∼ …

Platelets as autonomous drones for hemostatic and immune surveillance

JLY Li, A Zarbock, A Hidalgo - Journal of Experimental Medicine, 2017 - rupress.org
Platelets participate in many important physiological processes, including hemostasis and
immunity. However, despite their broad participation in these evolutionarily critical roles, the …

What salamanders have taught us about evolution

DB Wake - Annu. Rev. Ecol. Evol. Syst., 2009 - annualreviews.org
Taxon-based research in evolution permits the development of a multidimensional
approach, illustrated here with lessons learned from research on salamanders. The clade is …

Trim58 degrades Dynein and regulates terminal erythropoiesis

CS Thom, EA Traxler, E Khandros, JM Nickas… - Developmental cell, 2014 - cell.com
TRIM58 is an E3 ubiquitin ligase superfamily member implicated by genome-wide
association studies to regulate human erythrocyte traits. Here, we show that Trim58 …

A bird-like genome from a frog: Mechanisms of genome size reduction in the ornate burrowing frog, Platyplectrum ornatum

S Lamichhaney, R Catullo, JS Keogh… - Proceedings of the …, 2021 - National Acad Sciences
The diversity of genome sizes across the tree of life is of key interest in evolutionary biology.
Various correlates of variation in genome size, such as accumulation of transposable …

Genome size does not influence extinction risk in the world's amphibians

D Pincheira‐Donoso, LP Harvey, JV Johnson… - Functional …, 2023 - Wiley Online Library
Variation in genome size spans multiple orders of magnitude among animals. Despite the
longstanding debate regarding the adaptive value or costs of genomic complexity, genome …

Intrapopulation Genome Size Variation in D. melanogaster Reflects Life History Variation and Plasticity

LL Ellis, W Huang, AM Quinn, A Ahuja, B Alfrejd… - PLoS …, 2014 - journals.plos.org
We determined female genome sizes using flow cytometry for 211 Drosophila melanogaster
sequenced inbred strains from the Drosophila Genetic Reference Panel, and found …