Accurate and complete genomes from metagenomes

LX Chen, K Anantharaman, A Shaiber… - Genome …, 2020 - genome.cshlp.org
Genomes are an integral component of the biological information about an organism; thus,
the more complete the genome, the more informative it is. Historically, bacterial and …

Molluscan mitochondrial genomes break the rules

F Ghiselli, A Gomes-dos-Santos… - … of the Royal …, 2021 - royalsocietypublishing.org
The first animal mitochondrial genomes to be sequenced were of several vertebrates and
model organisms, and the consistency of genomic features found has led to a 'textbook …

[LIVRE][B] tRNAscan-SE: searching for tRNA genes in genomic sequences

PP Chan, TM Lowe - 2019 - Springer
Transfer RNAs are the largest, most complex non-coding RNA family, universal to all living
organisms. tRNAscan-SE has been the de facto tool for predicting tRNA genes in whole …

tRNAscan-SE 2.0: improved detection and functional classification of transfer RNA genes

PP Chan, BY Lin, AJ Mak, TM Lowe - Nucleic acids research, 2021 - academic.oup.com
Abstract tRNAscan-SE has been widely used for transfer RNA (tRNA) gene prediction for
over twenty years, developed just as the first genomes were decoded. With the massive …

CPGAVAS2, an integrated plastome sequence annotator and analyzer

L Shi, H Chen, M Jiang, L Wang, X Wu… - Nucleic acids …, 2019 - academic.oup.com
We previously developed a web server CPGAVAS for annotation, visualization and
GenBank submission of plastome sequences. Here, we upgrade the server into CPGAVAS2 …

A human gut bacterial genome and culture collection for improved metagenomic analyses

SC Forster, N Kumar, BO Anonye, A Almeida… - Nature …, 2019 - nature.com
Understanding gut microbiome functions requires cultivated bacteria for experimental
validation and reference bacterial genome sequences to interpret metagenome datasets …

High-quality de novo assembly of the apple genome and methylome dynamics of early fruit development

N Daccord, JM Celton, G Linsmith, C Becker… - Nature …, 2017 - nature.com
Using the latest sequencing and optical map** technologies, we have produced a high-
quality de novo assembly of the apple (Malus domestica Borkh.) genome. Repeat …

Genomes of subaerial Zygnematophyceae provide insights into land plant evolution

S Cheng, W **an, Y Fu, B Marin, J Keller, T Wu, W Sun… - Cell, 2019 - cell.com
The transition to a terrestrial environment, termed terrestrialization, is generally regarded as
a pivotal event in the evolution and diversification of the land plant flora that changed the …

High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq

A Behrens, G Rodschinka, DD Nedialkova - Molecular cell, 2021 - cell.com
Measurements of cellular tRNA abundance are hampered by pervasive blocks to cDNA
synthesis at modified nucleosides and the extensive similarity among tRNA genes. We …

TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS

X Zuo, J Zhou, Y Li, K Wu, Z Chen, Z Luo… - Nature structural & …, 2021 - nature.com
Amyotrophic lateral sclerosis (ALS) was initially thought to be associated with oxidative
stress when it was first linked to mutant superoxide dismutase 1 (SOD1). The subsequent …