Neuronal responses to physiological stress

K Kagias, C Nehammer, R Pocock - Frontiers in genetics, 2012 - frontiersin.org
Physiological stress can be defined as any external or internal condition that challenges the
homeostasis of a cell or an organism. It can be divided into three different aspects …

Combinational exposure to hydroxyatrazine increases neurotoxicity of polystyrene nanoparticles on Caenorhabditis elegans

Y Wang, X Yuan, R Zhou, Y Bu, D Wang - Science of The Total …, 2023 - Elsevier
Using Caenorhabditis elegans as an animal model, we investigated combinational effect
between 2-hydroxyatrazine (HA) and polystyrene nanoparticle (PS-NP) on function and …

The Intersection of Aging, Longevity Pathways, and Learning and Memory in C. elegans

GM Stein, CT Murphy - Frontiers in Genetics, 2012 - frontiersin.org
Our understanding of the molecular and genetic regulation of aging and longevity has been
greatly augmented through studies using the small model system, C. elegans. It is important …

[HTML][HTML] Synapse location during growth depends on glia location

Z Shao, S Watanabe, R Christensen, EM Jorgensen… - Cell, 2013 - cell.com
Synaptic contacts are largely established during embryogenesis and are then maintained
during growth. To identify molecules involved in this process, we conducted a forward …

A perspective on C. elegans neurodevelopment: from early visionaries to a booming neuroscience research

G Rapti - Journal of neurogenetics, 2020 - Taylor & Francis
The formation of the nervous system and its striking complexity is a remarkable feat of
development. C. elegans served as a unique model to dissect the molecular events in …

Age-progressive interplay of HSP-proteostasis, ECM-cell junctions and biomechanics ensures C. elegans astroglial architecture

F Coraggio, M Bhushan, S Roumeliotis, F Caroti… - Nature …, 2024 - nature.com
Tissue integrity is sensitive to temperature, tension, age, and is sustained throughout life by
adaptive cell-autonomous or extrinsic mechanisms. Safeguarding the remarkably-complex …

[HTML][HTML] Dystrophin induced cognitive impairment: mechanisms, models and therapeutic strategies

A Anand, R Tyagi, M Mohanty, M Goyal… - Annals of …, 2015 - ncbi.nlm.nih.gov
Existence of conserved domains in dystrophin and its associated complexes provide an
opportunity to understand the role of dystrophin associated signalling and its association …

[HTML][HTML] Neuronal aging: learning from C. elegans

CH Chen, YC Chen, HC Jiang, CK Chen… - Journal of Molecular …, 2013 - Springer
The heterogeneity and multigenetic nature of nervous system aging make modeling of it a
formidable task in mammalian species. The powerful genetics, simple anatomy and short life …

Cellular basis of learning and memory in the carotid body

OMS Gold, EN Bardsley, AP Ponnampalam… - Frontiers in Synaptic …, 2022 - frontiersin.org
The carotid body is the primary peripheral chemoreceptor in the body, and critical for
respiration and cardiovascular adjustments during hypoxia. Yet considerable evidence now …

The outer kinetochore components KNL-1 and Ndc80 complex regulate axon and neuronal cell body positioning in the C. elegans nervous system

VR Ouzounidis, M Green, CC van Capelle… - Molecular Biology of …, 2024 - Am Soc Cell Biol
The KMN (Knl1/Mis12/Ndc80) network at the kinetochore, primarily known for its role in
chromosome segregation, has been shown to be repurposed during neurodevelopment …