Role of oleic acid in immune system; mechanism of action; a review

C Carrillo Pérez, MM Cavia Camarero… - … , 2012, v. 27, n. 4 (julio …, 2012 - riubu.ubu.es
Introduction: Although n-3 polyunsaturated fatty acids have been widely described as
antiinflammatory fats, little is known about the role of oleic acid in immune system. Aim: The …

p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets: evidence that proline-directed …

RM Kramer, EF Roberts, SL Um… - Journal of Biological …, 1996 - jbc.org
The Ca 2+-sensitive 85-kDa cytosolic phospholipase A 2 (cPLA 2) is responsible for
thrombin-stimulated mobilization of arachidonic acid for the synthesis of thromboxane A 2 in …

Fatty acid metabolism of isolated mammalian cells

MD Rosenthal - Progress in Lipid Research, 1987 - Elsevier
Many cellular functions are crucially dependent on the dynamic nature of cellular
membranes. Fatty acids, and in particular polyunsaturated fatty acids, are an integral part of …

[HTML][HTML] Arachidonic acid inhibits myosin light chain phosphatase and sensitizes smooth muscle to calcium.

MC Gong, A Fuglsang, D Alessi, S Kobayashi… - Journal of Biological …, 1992 - Elsevier
Arachidonic acid (AA) increased, at constant Ca2+, the levels of force and 20-kDa myosin
light chain (MLC20) phosphorylation in permeabilized smooth muscle, and slowed …

Pancreatic and Snake Venom Phospholipases A2

M Waite - The phospholipases, 1987 - Springer
Chapters 6–8 covered the mammalian phospholipases that are cellular for the most part.
This chapter and the following chapters also include some mammalian phospholipases A 2; …

Mechanism of arachidonic acid liberation during ischemia in gerbil cerebral cortex

K Abe, K Kogure, H Yamamoto… - Journal of …, 1987 - Wiley Online Library
Once brain ischemia was induced in the gerbil cerebral fronto‐parietal cortex, serial
changes occurred in energy metabolites and various lipids. The amounts of inosi‐tol …

Translocation and phosphorylation of cytosolic phospholipase A2 in activated platelets

A McNicol, TS Shibou - Thrombosis research, 1998 - Elsevier
The release of arachidonic acid, and its subsequent conversion to thromboxane A2, is an
important component of platelet activation. The precise mechanism of arachidonic acid …

Alterations in individual molecular species of human platelet phospholipids during thrombin stimulation: electrospray ionization mass spectrometry-facilitated …

X Han, RA Gubitosi-Klug, BJ Collins, RW Gross - Biochemistry, 1996 - ACS Publications
Although the rapid thrombin-induced release of arachidonic acid in human platelets has
been known for over 20 years, the amount of arachidonic acid mass mobilized and the …

Evidence for a role for tyrosine phosphorylation of phospholipase Cγ2 in collagen-induced platelet cytosolic calcium mobilization

JL Daniel, C Dangelmaier, JB Smith - Biochemical Journal, 1994 - portlandpress.com
(1) The non-specific protein kinase C inhibitor, staurosporine, inhibited collagen-induced
increases in cytosolic free Ca2+ while having no effect on Ca2+ mobilization by other …

Effects of brazilin on the phospholipase A2 activity and changes of intracellular free calcium concentration in rat platelets

GS Hwang, JY Kim, TS Chang, SD Jeon, DS So… - Archives of Pharmacal …, 1998 - Springer
Abstract Brazilin {7, 11 b-dihydrobenz [b] indeno [1, 2-d] pyran-3, 6a, 9, 10 (6 H)-tetrol}
inhibited thrombin-, collagen-and ADP-induced aggregation of washed rat platelets …