Background: Anticoagulation for mechanical heart valves during pregnancy is essential to
prevent thromboembolic events. Each regimen has drawbacks with regard to maternal or …

Background Managing anticoagulation in pregnant women with mechanical heart valves
remains challenging. Our aim was to evaluate the effectiveness and safety of 4 regimens in …

Background The use of anticoagulant therapy during pregnancy is challenging because of
the potential for both fetal and maternal complications. This guideline focuses on the …

The continuation of warfarin throughout pregnancy in patients with a mechanical valve
prosthesis is a valid anticoagulation regimen, provided that warfarin dose does not exceed 5 …

One-third of women with heart disease use medication for the treatment of cardiovascular
disease (CVD) during pregnancy. Increased plasma volume, renal clearance, and liver …

Pregnancy is a hemostatic challenge: women are prone to thromboembolism during their
pregnancy and at the same time, especially during delivery, there is substantial risk of …

Thrombotic complications of pregnancy are a major cause of morbidity and mortality to the
mother and fetus. Pulmonary embolism is a leading cause of maternal death and accounts …

Background: Cardiac disease in pregnancy is a common problem in under-resourced
countries and a significant cause of maternal morbidity and mortality. A large proportion of …

Background Fetal exposure to maternal ingestion of warfarin is known to produce certain
dysmorphic features in the neonate, known as fetal warfarin syndrome (FWS). There is a …

Background Pregnancy is associated with several cardiocirculatory changes that can
significantly impact underlying cardiac disease. These changes include an increase in …