In pigs, the major histocompatibility complex (MHC), or swine leukocyte antigen (SLA)
complex, maps to Sus scrofa chromosome 7. It consists of three regions, the class I and …

Numerous genes for monogenic kidney diseases with classical patterns of inheritance, as
well as genes for complex kidney diseases that manifest in combination with environmental …

Membrane transporters play an essential role in the pharmacokinetics of drugs as they
mediate exchanges between biological compartments. Tacrolimus is characterized by wide …

Abstract The Sensitization in Transplantation: Assessment of Risk workgroup is a
collaborative effort of the American Society of Transplantation and the American Society of …

Background Kidney allograft failure is a common cause of end-stage renal disease. We
aimed to develop a dynamic artificial intelligence approach to enhance risk stratification for …

Background In the context of kidney transplantation, genomic incompatibilities between
donor and recipient may lead to allosensitization against new antigens. We hypothesized …

Antibody-mediated rejection (ABMR) is a leading cause of graft failure. Emerging evidence
suggests a significant contribution of natural killer (NK) cells to microvascular inflammation …

Although the gold standard of monitoring kidney transplant function relies on glomerular
filtration rate (GFR), little is known about GFR trajectories after transplantation, their …

Objective. To determine the frequency and distribution of ABO and Rh (D) antigens and,
additionally, investigate gene diversity and the structure of Mexican populations. Materials …

Renal transplant recipients have an increased risk of non-melanoma skin cancer (NMSC)
compared to in the general population. Here, we show polygenic risk scores (PRS) …