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[HTML][HTML] Circular RNAs: Characterization, cellular roles, and applications
CX Liu, LL Chen - Cell, 2022 - cell.com
Most circular RNAs are produced from the back-splicing of exons of precursor mRNAs.
Recent technological advances have in part overcome problems with their circular …
Recent technological advances have in part overcome problems with their circular …
The emerging roles of circRNAs in cancer and oncology
Over the past decade, circular RNAs (circRNAs) have emerged as a large class of primarily
non-coding RNA molecules, many of which have key roles in cancer development and …
non-coding RNA molecules, many of which have key roles in cancer development and …
Biogenesis and regulatory roles of circular RNAs
Covalently closed, single-stranded circular RNAs can be produced from viral RNA genomes
as well as from the processing of cellular housekee** noncoding RNAs and precursor …
as well as from the processing of cellular housekee** noncoding RNAs and precursor …
The expanding regulatory mechanisms and cellular functions of circular RNAs
LL Chen - Nature reviews Molecular cell biology, 2020 - nature.com
Many protein-coding genes in higher eukaryotes can produce circular RNAs (circRNAs)
through back-splicing of exons. CircRNAs differ from mRNAs in their production, structure …
through back-splicing of exons. CircRNAs differ from mRNAs in their production, structure …
Clinical delivery of circular RNA: lessons learned from RNA drug development
Circular RNAs (circRNA) represent a distinct class of covalently closed-loop RNA molecules,
which play diverse roles in regulating biological processes and disease states. The …
which play diverse roles in regulating biological processes and disease states. The …
The biogenesis, biology and characterization of circular RNAs
Circular RNAs (circRNAs) are covalently closed, endogenous biomolecules in eukaryotes
with tissue-specific and cell-specific expression patterns, whose biogenesis is regulated by …
with tissue-specific and cell-specific expression patterns, whose biogenesis is regulated by …
The biogenesis, functions, and challenges of circular RNAs
Covalently closed circular RNAs (circRNAs) are produced by precursor mRNA back-splicing
of exons of thousands of genes in eukaryotes. circRNAs are generally expressed at low …
of exons of thousands of genes in eukaryotes. circRNAs are generally expressed at low …
[HTML][HTML] Review on circular RNAs and new insights into their roles in cancer
X Tang, H Ren, M Guo, J Qian, Y Yang, C Gu - … and structural biotechnology …, 2021 - Elsevier
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
Circular RNA and its mechanisms in disease: from the bench to the clinic
B Han, J Chao, H Yao - Pharmacology & therapeutics, 2018 - Elsevier
The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …
to a new perspective regarding our understanding of cellular physiology and disease …
Circular RNA in cardiovascular disease
MA Altesha, T Ni, A Khan, K Liu… - Journal of cellular …, 2019 - Wiley Online Library
Circular RNA (circRNA) are endogenous transcripts that display differential expression
across species, developmental stages, and pathologies. Their lack of free ends confers …
across species, developmental stages, and pathologies. Their lack of free ends confers …