Slowing the progression of Alzheimer disease (AD) might be the greatest unmet medical
need of our time. Although one AD therapeutic has received a controversial accelerated …

Research on racial differences in Alzheimer disease (AD) dementia has increased in recent
years. Older African American individuals bear a disproportionate burden of AD and …

Latin American populations may present patterns of sociodemographic, ethnic and cultural
diversity that can defy current universal models of healthy aging. The potential combination …

Background and Objectives To determine the diagnostic accuracy of a plasma Aβ42/Aβ40
assay in classifying amyloid PET status across global research studies using samples …

Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy
function as well as the most common pathological conditions of the brain. Demographic …

Importance Underrepresentation of many racial/ethnic groups in Alzheimer disease (AD)
clinical trials limits generalizability of results and hinders opportunities to examine potential …

Introduction Although dementia prevalence differs by race, it remains unclear whether
cognition and neuropsychiatric symptom severity differ between Black and White individuals …

The United States has long made substantial investments in clinical research with the goal
of improving the health and well-being of our nation. There is no doubt that these …

Observational studies suggest that nutritional factors have a potential cognitive benefit.
However, systematic reviews of randomised trials of dietary and nutritional supplements …

Importance Social determinants of health, such as income, education, housing quality, and
employment, are associated with disparities in Alzheimer disease and health generally, yet …