Mitochondria are vital organelles with distinct morphological features and functional
properties. The dynamic network of mitochondria undergoes structural and functional …

Mitochondria form dynamic networks in the cell that are balanced by the flux of iterative
fusion and fission events of the organelles. It is now appreciated that mitochondrial fission …

We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …

Synapses enable neurons to communicate with each other and are therefore a prerequisite
for normal brain function. Presynaptically, this communication requires energy and …

James Parkinson first described the motor symptoms of the disease that took his name over
200 years ago. While our knowledge of many of the changes that occur in this condition has …

Alzheimer's disease (AD) is the most common cause of dementia and is currently one of the
biggest public health concerns in the world. Mitochondrial dysfunction in neurons is one of …

The brain is one of the most energy-consuming organs in the mammalian body, and
synaptic transmission is one of the major contributors. To meet these energetic …

Neuronal computation is energetically expensive. Consequently, the brain's limited energy
supply imposes constraints on its information processing capability. Most brain energy is …

Mitochondria, the cell's major energy producers, also act as signaling hubs, interacting with
other organelles both directly and indirectly. Despite having its own circular genome, the …

Estrogen facilitates higher cognitive functions by exerting effects on brain regions such as
the prefrontal cortex and hippocampus. Estrogen induces spinogenesis and synaptogenesis …