Crystal engineering of pharmaceutical cocrystals in the discovery and development of improved drugs
The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …
reactions in the solid state. A broad chemical definition of crystal engineering was published …
3D printing in personalized drug delivery: An overview of hot-melt extrusion-based fused deposition modeling
Advancements in pharmaceutical technologies have led to the personalization of therapies
over the last decade. Three-dimensional printing (3DP) is an emerging technique in the …
over the last decade. Three-dimensional printing (3DP) is an emerging technique in the …
Advanced pharmaceutical applications of hot-melt extrusion coupled with fused deposition modelling (FDM) 3D printing for personalised drug delivery
Three-dimensional printing, also known as additive manufacturing, is a fabrication process
whereby a 3D object is created layer-by-layer by depositing a feedstock material such as …
whereby a 3D object is created layer-by-layer by depositing a feedstock material such as …
Coupling hot melt extrusion and fused deposition modeling: Critical properties for successful performance
Interest in 3D printing for pharmaceutical applications has increased in recent years.
Compared to other 3D printing techniques, hot melt extrusion (HME)-based fused deposition …
Compared to other 3D printing techniques, hot melt extrusion (HME)-based fused deposition …
Overview of extensively employed polymeric carriers in solid dispersion technology
Solid dispersion is the preferred technology to prepare efficacious forms of BCS class-II/IV
APIs. To prepare solid dispersions, there exist a wide variety of polymeric carriers with …
APIs. To prepare solid dispersions, there exist a wide variety of polymeric carriers with …
Quality of FDM 3D printed medicines for pediatrics: considerations for formulation development, filament extrusion, printing process and printer design
J Quodbach, M Bogdahn, J Breitkreutz… - … Innovation & Regulatory …, 2021 - Springer
Abstract 3d printing is capable of providing dose individualization for pediatric medicines
and translating the precision medicine approach into practical application. In pediatrics …
and translating the precision medicine approach into practical application. In pediatrics …
Tinkering with mechanochemical tools for scale up
Mechanochemistry provides an environmentally benign platform to develop more
sustainable chemical processes by limiting raw materials, energy use, and waste generation …
sustainable chemical processes by limiting raw materials, energy use, and waste generation …
A systematic and robust assessment of hot-melt extrusion-based amorphous solid dispersions: Theoretical prediction to practical implementation
Amorphous solid dispersions (ASDs) have gained attention as a formulation strategy in
recent years, with the potential to improve the apparent solubility and, hence, the oral …
recent years, with the potential to improve the apparent solubility and, hence, the oral …
Hot melt extrusion paired fused deposition modeling 3D printing to develop hydroxypropyl cellulose based floating tablets of cinnarizine
Three-dimensional printing could serve as a platform to fabricate individualized medicines
and complex-structured solid dosage forms. Herein, hot melt extrusion was coupled with 3D …
and complex-structured solid dosage forms. Herein, hot melt extrusion was coupled with 3D …
Pharmaceutical approaches for enhancing solubility and oral bioavailability of poorly soluble drugs
I Nyamba, CB Sombie, M Yabre… - European Journal of …, 2024 - Elsevier
High solubility in water and physiological fluids is an indispensable requirement for the
pharmacological efficacy of an active pharmaceutical ingredient. Indeed, it is well …
pharmacological efficacy of an active pharmaceutical ingredient. Indeed, it is well …